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Share-based compensation, Plans Outstanding (Details)
12 Months Ended
Dec. 31, 2021
shares
Plan
Dec. 31, 2020
shares
Dec. 31, 2019
shares
Share-based compensation [Abstract]      
Number of equity-based instrument plans | Plan 4    
Share-based plans outstanding [Abstract]      
Number of options awarded (in shares) 1,110,914 1,073,027 1,053,305
Share Option Plan C1 [Member]      
Share-based plans outstanding [Abstract]      
Number of options awarded (in shares) 6,775,250    
Vesting conditions 4 years    
Contractual life of options 10 years    
2016 SOIP [Member] | Executives and Directors [Member]      
Share-based plans outstanding [Abstract]      
Number of options awarded (in shares) 2,643,984    
Contractual life of options 10 years    
2016 SOIP [Member] | Employees [Member]      
Share-based plans outstanding [Abstract]      
Number of options awarded (in shares) 1,354,431    
Vesting conditions 4 years    
Contractual life of options 10 years    
2016 SOIP, Vesting Condition 1 [Member] | Executives and Directors [Member]      
Share-based plans outstanding [Abstract]      
Vesting conditions 1 year    
2016 SOIP, Vesting Condition 2 [Member] | Executives and Directors [Member]      
Share-based plans outstanding [Abstract]      
Vesting conditions 3 years    
2016 SOIP, Vesting Condition 3 [Member] | Executives and Directors [Member]      
Share-based plans outstanding [Abstract]      
Vesting conditions 4 years