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Net Loss per Share - Anti-dilutive Securities (Details) - shares
12 Months Ended
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Securities excluded from the calculation of diluted net loss per share attributable to common stockholders      
Amount of antidilutive securities excluded from computation of earnings per share 3,814,552 8,791,372 8,840,359
Employee stock options      
Securities excluded from the calculation of diluted net loss per share attributable to common stockholders      
Amount of antidilutive securities excluded from computation of earnings per share 3,059,690 2,791,754 2,845,226
Restricted stock      
Securities excluded from the calculation of diluted net loss per share attributable to common stockholders      
Amount of antidilutive securities excluded from computation of earnings per share 722,646    
Common stock warrants      
Securities excluded from the calculation of diluted net loss per share attributable to common stockholders      
Amount of antidilutive securities excluded from computation of earnings per share 32,216 446,593 442,108
Preferred stock warrants      
Securities excluded from the calculation of diluted net loss per share attributable to common stockholders      
Amount of antidilutive securities excluded from computation of earnings per share   463,589 463,589
Redeemable convertible preferred stock      
Securities excluded from the calculation of diluted net loss per share attributable to common stockholders      
Amount of antidilutive securities excluded from computation of earnings per share   5,089,436 5,089,436