Collaborations - Summary of Company's Accompanying Consolidated Financial Statements Attributable to Transactions Arising From Collaboration Arrangements (Details) - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2022	Jun. 30, 2021	Jun. 30, 2022	Jun. 30, 2021	Dec. 31, 2021
Incyte
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Revenue recognized in the period	$ 4,230	$ 4,791	$ 8,632	$ 9,525
Balance at June 30, 2022	1,000		1,000
Incyte | Accounts Receivable
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Balance at January 1, 2022			1,634
Billings			5,603
Cash receipts			(6,237)
Incyte | Unbilled Receivables
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Balance at January 1, 2022			2,975
Accrued receivables			3,475
Billings			(4,578)
Balance at June 30, 2022	1,872		1,872
Incyte | Deferred Revenue
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Balance at January 1, 2022	59,043		59,043		$ 73,330
Foreign exchange			(5,655)
Revenue recognized in the period			(8,632)
Balance at June 30, 2022	59,043		59,043		73,330
Less: current portion	(16,552)		(16,552)
Non-current balance at June 30, 2022	42,491		42,491
Lilly
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Revenue recognized in the period	4,147	3,765	8,185
Lilly | Accounts Receivable
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Billings			2,137
Cash receipts			(2,137)
Lilly | Unbilled Receivables
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Balance at January 1, 2022			1,203
Accrued receivables	1,950
Billings			(2,137)
Balance at June 30, 2022	1,016		1,016
Lilly | Deferred Revenue
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Balance at January 1, 2022	17,301		17,301		27,353
Foreign exchange	(1,867)
Revenue recognized in the period			(8,185)
Balance at June 30, 2022	17,301		17,301		27,353
Less: current portion	(14,162)		(14,162)
Non-current balance at June 30, 2022	3,139		3,139
Other
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Revenue recognized in the period	0	162	222	352
Other | Accounts Receivable
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Balance at January 1, 2022			41
Billings			489
Cash receipts			(529)
Foreign exchange			(1)
Other | Unbilled Receivables
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Balance at January 1, 2022			453
Accrued receivables			49
Billings			(489)
Foreign exchange			(5)
Balance at June 30, 2022	8		8
Other | Deferred Revenue
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Balance at January 1, 2022					222
Revenue recognized in the period			(222)
Balance at June 30, 2022					222
Collaboration Agreement
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Revenue recognized in the period	8,377	$ 3,927	17,039	$ 352
Collaboration Agreement | Accounts Receivable
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Balance at January 1, 2022			1,675
Billings			8,229
Cash receipts			(8,903)
Foreign exchange			(1)
Balance at June 30, 2022	1,000		1,000
Collaboration Agreement | Unbilled Receivables
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Balance at January 1, 2022			4,631
Accrued receivables			5,474
Billings			(7,204)
Foreign exchange			(5)
Balance at June 30, 2022	2,896		2,896
Collaboration Agreement | Deferred Revenue
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Balance at January 1, 2022	76,344		76,344		100,905
Foreign exchange			(7,522)
Revenue recognized in the period			(17,039)
Balance at June 30, 2022	76,344		76,344		$ 100,905
Less: current portion	(30,714)		(30,714)
Non-current balance at June 30, 2022	$ 45,630		$ 45,630