Document Format Files
| Seq | Description | Document | Type | Size |
|---|---|---|---|---|
| 1 | S-1 | a2226129zs-1.htm | S-1 | 3401573 |
| 2 | EX-3.1 | a2226129zex-3_1.htm | EX-3.1 | 579684 |
| 3 | EX-4.4 | a2226129zex-4_4.htm | EX-4.4 | 672001 |
| 4 | EX-10.1 | a2226129zex-10_1.htm | EX-10.1 | 188304 |
| 5 | EX-10.4 | a2226129zex-10_4.htm | EX-10.4 | 200427 |
| 6 | EX-10.5 | a2226129zex-10_5.htm | EX-10.5 | 624621 |
| 7 | EX-10.6 | a2226129zex-10_6.htm | EX-10.6 | 343901 |
| 8 | EX-10.7 | a2226129zex-10_7.htm | EX-10.7 | 760934 |
| 9 | EX-10.8 | a2226129zex-10_8.htm | EX-10.8 | 438813 |
| 10 | EX-10.9 | a2226129zex-10_9.htm | EX-10.9 | 211928 |
| 11 | EX-10.10 | a2226129zex-10_10.htm | EX-10.10 | 409489 |
| 12 | EX-10.11 | a2226129zex-10_11.htm | EX-10.11 | 367563 |
| 13 | EX-10.12 | a2226129zex-10_12.htm | EX-10.12 | 45116 |
| 14 | EX-10.13 | a2226129zex-10_13.htm | EX-10.13 | 158901 |
| 15 | EX-10.14 | a2226129zex-10_14.htm | EX-10.14 | 38756 |
| 16 | EX-10.15 | a2226129zex-10_15.htm | EX-10.15 | 35194 |
| 17 | EX-10.16 | a2226129zex-10_16.htm | EX-10.16 | 36039 |
| 18 | EX-21.1 | a2226129zex-21_1.htm | EX-21.1 | 11921 |
| 19 | EX-23.1 | a2226129zex-23_1.htm | EX-23.1 | 2360 |
| 20 | EX-99.2 | a2226129zex-99_2.htm | EX-99.2 | 4462 |
| 21 | G182412LO19I001.GIF | g182412lo19i001.gif | GRAPHIC | 181251 |
| 22 | G182412LO19I002.GIF | g182412lo19i002.gif | GRAPHIC | 10173 |
| 23 | G182412LO19I003.GIF | g182412lo19i003.gif | GRAPHIC | 163182 |
| 24 | G182412LO19I004.GIF | g182412lo19i004.gif | GRAPHIC | 95627 |
| 25 | G182412LO19I005.GIF | g182412lo19i005.gif | GRAPHIC | 89932 |
| 26 | G182412LM13I001.GIF | g182412lm13i001.gif | GRAPHIC | 80543 |
| 27 | G182412LM13I002.GIF | g182412lm13i002.gif | GRAPHIC | 9931 |
| 28 | G182412LM13I003.GIF | g182412lm13i003.gif | GRAPHIC | 170045 |
| 29 | G182412LM13I004.GIF | g182412lm13i004.gif | GRAPHIC | 102172 |
| 30 | G182412LM13I005.GIF | g182412lm13i005.gif | GRAPHIC | 97320 |
| 31 | G182412LK21I001.GIF | g182412lk21i001.gif | GRAPHIC | 149144 |
| 32 | G182412LK21I002.GIF | g182412lk21i002.gif | GRAPHIC | 176458 |
| 33 | G182412LK23I001.GIF | g182412lk23i001.gif | GRAPHIC | 95856 |
| 34 | G182412LK23I002.GIF | g182412lk23i002.gif | GRAPHIC | 259118 |
| 35 | G182412LI13I001.GIF | g182412li13i001.gif | GRAPHIC | 148920 |
| 36 | G182412LI13I002.GIF | g182412li13i002.gif | GRAPHIC | 176458 |
| 37 | G182412LI13I003.GIF | g182412li13i003.gif | GRAPHIC | 95856 |
| 38 | G182412LI13I004.GIF | g182412li13i004.gif | GRAPHIC | 259118 |
| 39 | G182412LS01I001.JPG | g182412ls01i001.jpg | GRAPHIC | 3600 |
| 40 | G182412LS03I001.JPG | g182412ls03i001.jpg | GRAPHIC | 3600 |
| 41 | G182412LS05I001.JPG | g182412ls05i001.jpg | GRAPHIC | 3600 |
| 42 | G182412LS07I001.JPG | g182412ls07i001.jpg | GRAPHIC | 3600 |
| 43 | G182412LS09I001.JPG | g182412ls09i001.jpg | GRAPHIC | 3600 |
| 44 | G182412LS11I001.JPG | g182412ls11i001.jpg | GRAPHIC | 3600 |
| 45 | G166405.JPG | g166405.jpg | GRAPHIC | 11408 |
| 46 | G440313.JPG | g440313.jpg | GRAPHIC | 58101 |
| 47 | G368057.JPG | g368057.jpg | GRAPHIC | 1224 |
| 48 | G865179.JPG | g865179.jpg | GRAPHIC | 64529 |
| 49 | G872842.JPG | g872842.jpg | GRAPHIC | 40894 |
| 50 | G619469.JPG | g619469.jpg | GRAPHIC | 88697 |
| 51 | G920672.JPG | g920672.jpg | GRAPHIC | 41618 |
| 52 | G20877.JPG | g20877.jpg | GRAPHIC | 35027 |
| 53 | G58792.JPG | g58792.jpg | GRAPHIC | 49354 |
| 54 | G102035.JPG | g102035.jpg | GRAPHIC | 71452 |
| 55 | G305921.JPG | g305921.jpg | GRAPHIC | 91844 |
| 56 | G675414.JPG | g675414.jpg | GRAPHIC | 127368 |
| 57 | G286086.JPG | g286086.jpg | GRAPHIC | 91328 |
| 58 | G861286.JPG | g861286.jpg | GRAPHIC | 113805 |
| 59 | G888720.JPG | g888720.jpg | GRAPHIC | 113293 |
| 60 | G208748.JPG | g208748.jpg | GRAPHIC | 34795 |
| 61 | G704151.JPG | g704151.jpg | GRAPHIC | 76677 |
| 62 | G862225.JPG | g862225.jpg | GRAPHIC | 56560 |
| 63 | G633413.JPG | g633413.jpg | GRAPHIC | 43355 |
| 64 | G283637.JPG | g283637.jpg | GRAPHIC | 102478 |
| 65 | G605185.JPG | g605185.jpg | GRAPHIC | 103444 |
| 66 | G482667.JPG | g482667.jpg | GRAPHIC | 77950 |
| 67 | G199005.JPG | g199005.jpg | GRAPHIC | 66512 |
| 68 | G253352.JPG | g253352.jpg | GRAPHIC | 67304 |
| 69 | G647391.JPG | g647391.jpg | GRAPHIC | 55789 |
| 70 | G483555.JPG | g483555.jpg | GRAPHIC | 54159 |
| 71 | G609503.JPG | g609503.jpg | GRAPHIC | 23029 |
| 72 | G161154.JPG | g161154.jpg | GRAPHIC | 40308 |
| 73 | G344946.JPG | g344946.jpg | GRAPHIC | 49887 |
| 74 | G126339.JPG | g126339.jpg | GRAPHIC | 76962 |
| 75 | G982502.JPG | g982502.jpg | GRAPHIC | 72237 |
| 76 | G897000.JPG | g897000.jpg | GRAPHIC | 154768 |
| 77 | G1029008.JPG | g1029008.jpg | GRAPHIC | 1247 |
| Complete submission text file | 0001047469-15-007900.txt | 14791017 |
IRS No.: 000000000 | State of Incorp.: E9 | Fiscal Year End: 1231
Type: S-1 | Act: 33 | File No.: 333-207459 | Film No.: 151162066
SIC: 2834 Pharmaceutical Preparations
Office of Life Sciences
