Condensed Consolidated Statements of Cash Flows - USD ($) $ in Thousands		6 Months Ended
		Jun. 30, 2025	Jun. 30, 2024
Cash flow from operating activities
Net loss		$ (129,323)	$ (129,557)
Adjustments to reconcile net loss to net cash used in operating activities:
Stock-based compensation expense		5,643	12,595
Depreciation		3,751	2,829
Loss on disposal of fixed assets		2,193	0
Net amortization of premiums and discounts on marketable securities		(840)	(3,596)
Interest related to sale of future revenues		4,236	0
Impairment of held for sale assets		3,724	0
Other non-cash items		(390)	(415)
Changes in operating assets and liabilities:
Accounts receivable		15,678	9,943
Prepaid expenses and other current assets		(418)	535
Right-of-use assets		8,694	(3,271)
Other non-current assets		1,025	443
Accounts payable		1,231	5,967
Accrued expenses		2,271	(6,538)
Accrued interest on sale of future revenues		(2,128)	0
Deferred revenue		(6,221)	0
Operating lease liabilities		(9,048)	2,162
Other non-current liabilities		1,911	1,969
Net cash used in operating activities		(98,011)	(106,934)
Cash flow from investing activities
Purchases of property and equipment		(114)	(5,365)
Proceeds from the sale of equipment		151	0
Purchases of marketable securities		0	(86,221)
Proceeds from maturities of marketable securities		99,000	138,795
Net cash provided by investing activities		99,037	47,209
Cash flow from financing activities
Repayment on sale of future revenues		(2,872)	0
Proceeds from issuance of common stock from at the market equity offering		8,619	0
Proceeds from exercise of stock options		0	192
Proceeds from issuance of common stock under employee stock purchase plan		228	322
Net cash provided by financing activities		5,975	514
Net increase (decrease) in cash, cash equivalents, and restricted cash		7,001	(59,211)
Cash, cash equivalents, and restricted cash, beginning of period		135,418	127,529
Cash, cash equivalents, and restricted cash, end of period		142,419	68,318
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Continuing Operation [Abstract]
Cash and cash equivalents, end of period		138,542	64,441
Restricted cash	[1]	3,877	3,877
Cash, cash equivalents, and restricted cash, end of period		142,419	68,318
Supplemental disclosure of cash and non-cash activities:
Fixed asset additions included in accounts payable and accrued expenses		0	54
Cash paid in connection with operating lease liabilities		11,048	7,683
Remeasurement of operating lease liabilities and right-of-use assets due to lease modification		766	794
Commencement of right-of-use asset		0	7,844
Non-cash termination of right-of-use asset		$ 4,849	$ 0

[1] 1 As of June 30, 2025 and June 30, 2024, restricted cash of $3,877 and $3,877 was included in Restricted cash and other non-current assets on the Consolidated Balance Sheet, respectively.