Condensed Consolidated Statements of Operations - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2022	Sep. 30, 2021	Sep. 30, 2022	Sep. 30, 2021
Condensed Consolidated Statements of Operations
Collaboration and other research and development revenues	$ 42	$ 6,197	$ 13,176	$ 13,075
Revenue type	us-gaap:ServiceMember	us-gaap:ServiceMember	us-gaap:ServiceMember	us-gaap:ServiceMember
Operating expenses:
Research and development	$ 41,326	$ 29,265	$ 122,960	$ 104,954
General and administrative	16,236	16,185	52,720	59,657
Total operating expenses	57,562	45,450	175,680	164,611
Operating loss	(57,520)	(39,253)	(162,504)	(151,536)
Other income, net:
Other income, net	1	19	4	38
Interest income, net	1,793	152	2,806	432
Total other income, net	1,794	171	2,810	470
Net loss	$ (55,726)	$ (39,082)	$ (159,694)	$ (151,066)
Net loss per share, basic (in dollars per share)	$ (0.81)	$ (0.57)	$ (2.33)	$ (2.24)
Net loss per share, diluted (in dollars per share)	$ (0.81)	$ (0.57)	$ (2.33)	$ (2.24)
Weighted-average common shares outstanding, basic (in shares)	68,736,125	68,219,742	68,621,574	67,371,246
Weighted-average common shares outstanding, diluted (in shares)	68,736,125	68,219,742	68,621,574	67,371,246