Condensed Consolidated Balance Sheets - USD ($) $ in Thousands	Sep. 30, 2022	Dec. 31, 2021
Current assets:
Cash and cash equivalents	$ 210,704	$ 203,519
Marketable securities	208,913	296,326
Accounts receivable	120	267
Prepaid expenses and other current assets	6,892	7,198
Total current assets	426,629	507,310
Marketable securities	58,844	120,071
Property and equipment, net	15,494	17,118
Right-of-use assets	22,532	26,173
Restricted cash and other non-current assets	7,530	6,811
Total assets	531,029	677,483
Current liabilities:
Accounts payable	6,836	5,050
Accrued expenses	19,259	20,192
Deferred revenue, current	4,221	11,333
Operating lease liabilities	11,973	10,309
Total current liabilities	42,289	46,884
Operating lease liabilities, net of current portion	9,328	16,069
Deferred revenue, net of current portion	64,667	60,888
Total liabilities	116,284	123,841
Stockholders' equity
Preferred stock, $0.0001 par value per share: 5,000,000 shares authorized; no shares issued or outstanding
Common stock, $0.0001 par value per share: 195,000,000 shares authorized; 68,761,729 and 68,489,257 shares issued, and 68,761,729 and 68,435,257 shares outstanding at September 30, 2022 and December 31, 2021, respectively	7	7
Additional paid-in capital	1,436,422	1,411,827
Accumulated other comprehensive loss	(4,291)	(493)
Accumulated deficit	(1,017,393)	(857,699)
Total stockholders' equity	414,745	553,642
Total liabilities and stockholders' equity	$ 531,029	$ 677,483