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Summary Of Significant Accounting Policies - Warrants to Purchase Convertible Preferred Stock (Details)
1 Months Ended 3 Months Ended 10 Months Ended 12 Months Ended 20 Months Ended 32 Months Ended
Jul. 31, 2017
USD ($)
May 31, 2016
USD ($)
Dec. 31, 2017
USD ($)
Sep. 30, 2017
USD ($)
Jun. 30, 2017
USD ($)
Mar. 31, 2017
USD ($)
Dec. 31, 2016
USD ($)
Sep. 30, 2016
USD ($)
Jun. 30, 2016
USD ($)
Mar. 31, 2016
USD ($)
Dec. 31, 2017
USD ($)
Dec. 31, 2017
USD ($)
item
Dec. 31, 2016
USD ($)
Dec. 31, 2015
USD ($)
Dec. 31, 2017
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Dec. 31, 2017
USD ($)
Recent Accounting Pronouncements                                
Number of Revenue Agreements | item                       3        
Collaboration and other research and development revenues     $ 3,667,000 $ 6,282,000 $ 3,097,000 $ 682,000 $ 898,000 $ 962,000 $ 3,388,000 $ 805,000   $ 13,728,000 $ 6,053,000 $ 1,629,000    
Adjustment to valuation allowance                       19,000,000        
ASU 2016-09                                
Recent Accounting Pronouncements                                
Adjustment to valuation allowance                       179,000        
Juno Therapeutics | Collaboration and License Agreement                                
Recent Accounting Pronouncements                                
Collaboration and other research and development revenues                       4,900,000 $ 5,700,000 $ 1,600,000   $ 12,200,000
Milestone payment received under license agreement $ 2,500,000 $ 2,500,000                            
Cystic Fibrosis Foundation Therapeutics, Inc. | Development award agreement                                
Recent Accounting Pronouncements                                
Collaboration and other research and development revenues                             $ 300,000  
Allergan | Strategic Alliance                                
Recent Accounting Pronouncements                                
Collaboration and other research and development revenues                     $ 8,800,000 $ 8,800,000