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Condensed Statements of Cash Flows - USD ($)
$ in Thousands
6 Months Ended 12 Months Ended
Jun. 30, 2025
Jun. 30, 2024
Dec. 31, 2024
Cash flows from operating activities      
Net loss $ (102,630) $ (67,354)  
Adjustments to reconcile net loss to net cash used in operating activities      
Stock-based compensation expense 11,944 12,048  
Vesting of common stock warrants in return for services   44  
Change in fair value of derivative liability (76) 13  
Depreciation and amortization 2,217 2,367  
Amortization of right-of-use assets 1,425 851  
Net accretion of discount on marketable securities (2,433) (3,092)  
Changes in operating assets and liabilities      
Prepaid expenses and other current assets (7) (2,330)  
Other assets (5,129) (1,636)  
Accounts payable 4,314 (83)  
Accrued and other liabilities 798 785  
Deferred revenue (29) 72  
Operating lease liabilities (1,529) (1,016)  
Net cash used in operating activities (91,135) (59,331)  
Cash flows from investing activities      
Purchase of marketable securities (249,480) (374,084)  
Maturities of marketable securities 268,273 38,346  
Acquisition of property and equipment (697) (1,059)  
Net cash provided by (used in) investing activities 18,096 (336,797)  
Cash flows from financing activities      
Issuance of common stock upon exercise of stock options and warrants 2 3,963  
Issuance of common stock - 2020 ESPP 860 707  
Net cash provided by financing activities 862 336,081  
Net decrease in cash and cash equivalents (72,177) (60,047)  
Cash and cash equivalents, beginning of period 149,336 249,108 $ 249,108
Cash and cash equivalents, end of period $ 77,159 189,061 $ 149,336
Supplemental disclosures of noncash investing and financing information      
Purchases of property and equipment in accounts payable and accrued and other liabilities   177  
Public offering      
Cash flows from financing activities      
Issuance of common stock under the offering program, net of issuance costs   316,148  
ATM Offering Program      
Cash flows from financing activities      
Issuance of common stock under the offering program, net of issuance costs   $ 15,263