Research and Collaboration Arrangements - Summary of Collaboration and License Revenue (Details) - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2024	Jun. 30, 2023	Jun. 30, 2024	Jun. 30, 2023
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Total revenue	$ 5	$ 239	$ 33	$ 538
Collaboration and License Revenue
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Total revenue	5	239	33	538
Collaboration and License Revenue | uniQure
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Total revenue	0	230	0	525
Collaboration and License Revenue | Cystic Fibrosis Foundation
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Total revenue	$ 5	$ 9	$ 33	$ 13