Stock-Based Compensation (Tables)

12 Months Ended

Sep. 30, 2022

Share-based Compensation

Schedule of stock-based compensation expense

	Year ended September 30,
	2022		2021
Research and development	$	2,691,330	$	953,328
General and administrative		5,019,474		3,933,959
	$	7,710,804	$	4,887,287

Schedule of performance-based stock units activity

				Weighted
				Average
	Number	Base		Remaining
	of	Price		Contractual	Aggregate
	PSUs	Per PSU		Term (Years)	Intrinsic Value
Balance at October 1, 2020	2,470	$	49.97
Forfeitures	—		—
Balance at September 30, 2021	2,470	$	49.97
Forfeitures	—		—
Balance at September 30, 2022	2,470	$	49.97	2.0	$	—
Vested and exercisable at September 30, 2022	2,470	$	49.97	2.0	$	—
Vested and expected to vest at September 30, 2022	2,470	$	49.97	2.0	$	—

Stock options

Share-based Compensation

Schedule of stock option activity

				Weighted
				Average
		Weighted		Remaining
	Number of	Average		Contractual	Aggregate
	Shares	Exercise Price		Term (Years)	Intrinsic Value
Balance at October 1, 2020	3,762,143	$	2.01
Granted	12,461,645		1.29
Forfeited or expired	(113,773)		0.76
Balance at September 30, 2021	16,110,015		1.46
Granted	4,039,566		1.60
Exercised	(25,000)		0.71		$	38,960
Balance at September 30, 2022	20,124,581	$	1.49	8.3	$	4,521,960
Exercisable	8,353,802	$	1.53	7.9	$	2,067,210
Vested and expected to vest at September 30, 2022	20,124,581	$	1.49	8.3	$	4,521,960

Schedule of option assumptions

	Year ended September 30,
	2022		2021
Risk-free interest rate	1.77	%	0.58	%
Expected term (years)	6.0		6.0
Expected volatility	95.3	%	94.5	%
Expected dividend yield	—		—

Performance-based stock options

Share-based Compensation

Schedule of stock option activity

				Weighted
				Average
		Weighted		Remaining
	Number of	Average		Contractual	Aggregate
	Shares	Exercise Price		Term (Years)	Intrinsic Value
Balance at October 1, 2020	—	$	—
Granted	1,000,000		2.42
Balance at September 30, 2021	1,000,000		2.42
Granted	1,900,000		1.44
Forfeited or expired	(2,200,000)		1.89
Balance at September 30, 2022	700,000	$	1.44	9.2	$	—
Exercisable	700,000	$	1.44	9.2	$	—
Vested and expected to vest at September 30, 2022	700,000	$	1.44	9.2	$	—

Schedule of option assumptions

	Year ended September 30,
	2022		2021
Risk-free interest rate	1.26	%	0.88	%
Expected term (years)	5.2		5.4
Expected volatility	91.5	%	93.1	%
Expected dividend yield	—		—