X0306 4 2022-08-11 0 0001649989 Outlook Therapeutics, Inc. OTLK 0001656082 Haller Julia A C/O OUTLOOK THERAPEUTICS, INC. 485 ROUTE 1 SOUTH, BLDG F, SUITE 320 ISELIN NJ 08830 1 0 0 0 Stock Option (Right to Buy) 1.15 2022-08-11 4 A 0 25000 0.00 A 2032-08-11 Common Stock 25000 25000 D The options were granted under the Issuer's 2015 Equity Incentive Plan (the "2015 Plan") and shall vest in three equal installments on each of August 11, 2023, August 11, 2024 and August 11, 2025, subject to the Reporting Person providing continuous service to the Issuer on each such date and subject to acceleration upon a Change in Control as defined in the 2015 Plan. /s/ Lawrence Kenyon, Attorney-in-Fact 2022-08-15