X0306 4 2020-10-01 0 0001649989 Outlook Therapeutics, Inc. OTLK 0001718004 Haddadin Yezan Munther C/O OUTLOOK THERAPEUTICS, INC. 4260 US ROUTE 1 MONMOUTH JUNCTION NJ 08852 1 0 0 0 Stock Option (Right to Buy) 0.71 2020-10-01 4 A 0 290372 0.00 A 2030-10-01 Common Stock 290372 290372 D Stock Option (Right to Buy) 0.7052 2020-10-05 4 A 0 160474 0.5141 A 2030-10-05 Common Stock 160474 160474 D The options were granted under the Issuer's 2015 Equity Incentive Plan (the "2015 Plan") and shall vest in full on October 1, 2021, subject to the Reporting Person providing continuous service to the Issuer on such date and subject to acceleration upon a Change in Control as defined in the 2015 Plan, subject to the Reporting Person providing continuous service to the Issuer through such event. The options were granted under the 2015 Plan in lieu of $82,500 cash fees payable under the Issuers's non-employee Director compensation program and vest in four equal quarterly installments on the last day of each fiscal quarter such that they are vested in full on September 30, 2021, subject to the Reporting Person providing continuous service to the Issuer on such date and subject to acceleration upon a Change in Control as defined in the 2015 Plan. /s/ Lawrence Kenyon, Attorney-in-Fact 2020-10-05