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Condensed Consolidated Statements of Cash Flows - USD ($)
shares in Thousands, $ in Thousands
9 Months Ended
Sep. 30, 2024
Sep. 30, 2023
Operating activities    
Net loss $ (217,310) $ (143,045)
Adjustments to reconcile net loss to net cash used in operating activities:    
Stock-based compensation expense 29,126 23,879
Depreciation and amortization 1,180 1,341
Non-cash accretion of other current liability 2,966  
Non-cash interest expense 12,190 9,342
Non-cash accretion & amortization of short-term investments (6,027)  
Non-cash rent expense 289 294
Change in fair value of embedded derivative liability (1,300) (150)
Gain on settlement of forward contract (8,900)  
Acquired IPR&D assets classified as investing activities 92,385 5,667
Changes in operating assets and liabilities:    
Accounts receivable (4,439) (8,317)
Inventory (5,271) (4,845)
Prepaid expenses and other current assets 181 (2,367)
Deferred revenue   (148)
Other long-term assets, net 3,157 1,660
Accounts payable, accrued expenses and other liabilities 6,739 9,915
Net cash used in operating activities (95,034) (106,774)
Investing activities    
Purchases of short-term investments (201,935) (314,265)
Maturities of short-term investments 173,105 291,675
Acquisition of IPR&D assets (40,500) (5,667)
Purchases of property and equipment   (48)
Net cash used in investing activities (69,330) (28,305)
Financing activities    
Repayment of deferred royalty obligation (9,092) (4,824)
Proceeds from the exercise of stock options 12,986 2,471
Proceeds from issuance of common stock from ESPP 1,270 1,053
Net proceeds from issuance of common stock   48,875
Proceeds from royalty financing agreement, net of issuance costs   24,370
Gain on settlement of forward contract 8,900  
Proceeds from Series A Preferred Stock, net of issuance costs 138,850  
Net cash provided by (used in) financing activities 152,914 71,945
Effect of exchange rates on cash (975) 50
Net increase (decrease) in cash, cash equivalents and restricted cash (12,426) (63,084)
Cash, cash equivalents and restricted cash at beginning of period 60,409 128,005
Cash, cash equivalents and restricted cash at end of period 47,983 $ 64,921
Supplemental disclosure of non-cash investing and financing activities:    
Non-current liability issued in exchange for the acquisition of IPR&D $ 33,669  
Issuance of common stock in exchange for IPR&D 18,716  
Accretion of preferred stock dividends $ 2,631