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Condensed Consolidated Statements of Convertible Preferred Stock & Stockholders' Equity - USD ($)
$ in Thousands
Common Stock
Additional Paid-In Capital
Accumulated Other Comprehensive Income (Loss)
Accumulated Deficit
Common stock reserved for the conversion of Series A convertible preferred stock
Total
Beginning balance at Dec. 31, 2022 $ 56 $ 974,356 $ (92) $ (710,058)   $ 264,262
Beginning balance (in shares) at Dec. 31, 2022 56,612,429          
Increase (Decrease) in Stockholders' Equity            
Stock-based compensation expense   6,376       6,376
Issuance of common stock in connection with ESPP   665       665
Issuance of common stock in connection with ESPP (in shares) 32,169          
Issuance of common stock in connection with exercise of stock options and vesting of restricted stock units   553       553
Issuance of common stock in connection with exercise of stock options and vesting of restricted stock units (in shares) 207,806          
Foreign currency translation adjustment     21     21
Net unrealized losses on short-term investments     65     65
Net loss       (52,179)   (52,179)
Ending balance at Mar. 31, 2023 $ 56 981,950 (6) (762,237)   219,763
Ending balance (in shares) at Mar. 31, 2023 56,852,404          
Beginning balance at Dec. 31, 2022 $ 56 974,356 (92) (710,058)   264,262
Beginning balance (in shares) at Dec. 31, 2022 56,612,429          
Increase (Decrease) in Stockholders' Equity            
Foreign currency translation adjustment           49
Net loss           (143,045)
Ending balance at Sep. 30, 2023 $ 59 1,050,631 (113) (853,103)   197,474
Ending balance (in shares) at Sep. 30, 2023 59,089,352          
Beginning balance at Mar. 31, 2023 $ 56 981,950 (6) (762,237)   219,763
Beginning balance (in shares) at Mar. 31, 2023 56,852,404          
Increase (Decrease) in Stockholders' Equity            
Stock-based compensation expense   8,891       8,891
Issuance of common stock in connection with exercise of stock options and vesting of restricted stock units $ 1 341       342
Issuance of common stock in connection with exercise of stock options and vesting of restricted stock units (in shares) 43,664          
Foreign currency translation adjustment     (48)     (48)
Net unrealized losses on short-term investments     40     40
Net loss       (46,703)   (46,703)
Ending balance at Jun. 30, 2023 $ 57 991,182 (14) (808,940)   182,285
Ending balance (in shares) at Jun. 30, 2023 56,896,068          
Increase (Decrease) in Stockholders' Equity            
Stock-based compensation expense   8,612       8,612
Issuance of common stock in connection with ESPP   388       388
Issuance of common stock in connection with ESPP (in shares) 17,650          
Issuance of common stock in connection with exercise of stock options and vesting of restricted stock units   1,576       1,576
Issuance of common stock in connection with exercise of stock options and vesting of restricted stock units (in shares) 156,389          
Issuance of common stock upon completion of public offering, net of offering costs $ 2 48,873       48,875
Issuance of common stock upon completion of public offering, net of offering costs (in shares) 2,019,245          
Foreign currency translation adjustment     76     76
Net unrealized losses on short-term investments     (175)     (175)
Net loss       (44,163)   (44,163)
Ending balance at Sep. 30, 2023 $ 59 1,050,631 (113) (853,103)   197,474
Ending balance (in shares) at Sep. 30, 2023 59,089,352          
Temporary Equity            
Issuance of Series A Preferred Stock, net of $2,250 of issuance costs (in shares)         0  
Beginning balance (in shares) at Dec. 31, 2023         0  
Beginning balance at Dec. 31, 2023 $ 59 1,064,302 134 (894,736)   169,759
Beginning balance (in shares) at Dec. 31, 2023 59,426,559          
Increase (Decrease) in Stockholders' Equity            
Stock-based compensation expense   7,767       7,767
Issuance of common stock in connection with ESPP   673       673
Issuance of common stock in connection with ESPP (in shares) 28,495          
Issuance of common stock in connection with exercise of stock options and vesting of restricted stock units $ 1 6,352       6,353
Issuance of common stock in connection with exercise of stock options and vesting of restricted stock units (in shares) 1,077,271          
Issuance of common stock as consideration for LGC license   18,716       18,716
Issuance of common stock as consideration for LGC license (in shares) 432,143          
Foreign currency translation adjustment     (71)     (71)
Unrealized loss on marketable securities     (244)     (244)
Net loss       (141,372)   (141,372)
Ending balance at Mar. 31, 2024 $ 60 1,097,810 (181) (1,036,108)   61,581
Ending balance (in shares) at Mar. 31, 2024 60,964,468          
Beginning balance (in shares) at Dec. 31, 2023         0  
Temporary Equity            
Accrued dividends on convertible preferred stock           2,631
Ending balance at Sep. 30, 2024         $ 141,481 141,481
Ending balance (in shares) at Sep. 30, 2024         150,000  
Beginning balance at Dec. 31, 2023 $ 59 1,064,302 134 (894,736)   169,759
Beginning balance (in shares) at Dec. 31, 2023 59,426,559          
Increase (Decrease) in Stockholders' Equity            
Foreign currency translation adjustment           (975)
Net loss           (217,310)
Ending balance at Sep. 30, 2024 $ 61 1,123,768 (604) (1,112,010)   11,215
Ending balance (in shares) at Sep. 30, 2024 61,436,251          
Temporary Equity            
Issuance of Series A Preferred Stock, net of $2,250 of issuance costs         $ 138,850  
Accrued dividends on convertible preferred stock         1,302  
Ending balance at Jun. 30, 2024         $ 140,152  
Ending balance (in shares) at Jun. 30, 2024         150,000  
Beginning balance at Mar. 31, 2024 $ 60 1,097,810 (181) (1,036,108)   61,581
Beginning balance (in shares) at Mar. 31, 2024 60,964,468          
Increase (Decrease) in Stockholders' Equity            
Stock-based compensation expense   10,358       10,358
Issuance of common stock in connection with exercise of stock options and vesting of restricted stock units   1,403       1,403
Issuance of common stock in connection with exercise of stock options and vesting of restricted stock units (in shares) 131,481          
Accretion of preferred stock dividends   (1,302)       (1,302)
Foreign currency translation adjustment     (302)     (302)
Unrealized loss on marketable securities     (134)     (134)
Net loss       (32,261)   (32,261)
Ending balance at Jun. 30, 2024 $ 60 1,108,269 (617) (1,068,369)   39,343
Ending balance (in shares) at Jun. 30, 2024 61,095,949          
Temporary Equity            
Issuance of Series A Preferred Stock, net of $2,250 of issuance costs (in shares)         150,000  
Accrued dividends on convertible preferred stock         $ 1,329 1,329
Ending balance at Sep. 30, 2024         $ 141,481 141,481
Ending balance (in shares) at Sep. 30, 2024         150,000  
Increase (Decrease) in Stockholders' Equity            
Stock-based compensation expense   11,001       11,001
Issuance of common stock in connection with ESPP   597       597
Issuance of common stock in connection with ESPP (in shares) 16,059          
Issuance of common stock in connection with exercise of stock options and vesting of restricted stock units $ 1 5,230       5,231
Issuance of common stock in connection with exercise of stock options and vesting of restricted stock units (in shares) 324,243          
Accretion of preferred stock dividends   (1,329)       (1,329)
Foreign currency translation adjustment     (602)     (602)
Net unrealized losses on short-term investments     615     615
Net loss       (43,641)   (43,641)
Ending balance at Sep. 30, 2024 $ 61 $ 1,123,768 $ (604) $ (1,112,010)   $ 11,215
Ending balance (in shares) at Sep. 30, 2024 61,436,251          
Temporary Equity            
Issuance of Series A Preferred Stock, net of $2,250 of issuance costs (in shares)         150,000