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Condensed Consolidated Statements of Cash Flows - USD ($)
shares in Thousands, $ in Thousands
6 Months Ended
Jun. 30, 2024
Jun. 30, 2023
Operating activities    
Net loss $ (173,633) $ (98,882)
Adjustments to reconcile net loss to net cash used in operating activities:    
Stock-based compensation expense 18,125 15,267
Depreciation and amortization 795 899
Non-cash interest expense 7,987 6,194
Non-cash accretion & amortization of short-term investments (3,562) (4,299)
Non-cash accretion of non-current liability 1,927  
Non-cash rent expense 181 192
Change in fair value of embedded derivative liability (790) (20)
Gain on settlement of forward contract (8,900)  
Acquired IPR&D assets classified as investing activities 92,385 5,650
Changes in operating assets and liabilities:    
Accounts receivable (2,731) (7,607)
Inventory (3,370) (3,260)
Prepaid expenses and other current assets 287 1,540
Deferred revenue   (148)
Other long-term assets, net 2,249 1,123
Accounts payable, accrued expenses and other liabilities (769) 5,828
Net cash used in operating activities (69,819) (77,523)
Investing activities    
Purchases of short-term investments (66,312) (145,078)
Maturities of short-term investments 127,800 217,175
Acquisition of IPR&D assets (40,000) (5,395)
Purchases of property and equipment   (47)
Net cash provided by investing activities 21,488 66,655
Financing activities    
Repayment of deferred royalty obligation (5,756) (2,657)
Proceeds from the exercise of stock options 7,755 894
Proceeds from issuance of common stock from ESPP 673 665
Gain on settlement of forward contract 8,900  
Proceeds from Series A Preferred Stock, net of issuance costs 138,850  
Net cash provided by (used in) financing activities 150,422 (1,098)
Effect of exchange rates on cash (372) (27)
Net increase (decrease) in cash, cash equivalents and restricted cash 101,719 (11,993)
Cash, cash equivalents and restricted cash at beginning of period 60,409 128,005
Cash, cash equivalents and restricted cash at end of period 162,128 116,012
Supplemental disclosure of non-cash investing and financing activities:    
Non-current liability issued in exchange for the acquisition of IPR&D $ 33,669  
Issuance of common stock in exchange for IPR&D 18,716  
Accretion of preferred stock dividends $ 1,302  
Holdback payable associated with acquisition of IPR&D assets, in accrued expenses   500
Transaction costs associated with acquisition of IPR&D assets, in accounts payable   $ 255