CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2023	Mar. 31, 2022
CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS
Product revenue, net	$ 11,469	$ 1,498
Costs and expenses:
Cost of sales	1,421	230
Research and development	37,945	32,510
Selling, general, and administrative	24,634	21,449
Total costs and expenses	64,000	54,189
Loss from operations	(52,531)	(52,691)
Other income:
Other expense, net	(27)	(233)
Interest expense	(3,061)
Interest income	3,440	160
Total other income (expense), net	352	(73)
Net loss	$ (52,179)	$ (52,764)
Net loss per share, basic (in dollars per share)	$ (0.92)	$ (1.05)
Net loss per share, diluted (in dollars per share)	$ (0.92)	$ (1.05)
Weighted-average common shares outstanding, basic (in shares)	56,708,975	50,326,627
Weighted-average common shares outstanding, diluted (in shares)	56,708,975	50,326,627
Other comprehensive loss:
Net loss	$ (52,179)	$ (52,764)
Foreign currency translation adjustment	21
Unrealized gain (loss), net on marketable securities	65	(628)
Comprehensive loss	$ (52,093)	$ (53,392)