Summary of Significant Accounting Policies - License Agreements (Details) - Rare Stone Group Ltd. $ in Thousands	1 Months Ended	3 Months Ended				12 Months Ended
	Dec. 31, 2021 USD ($) item shares	Mar. 31, 2023 USD ($)	Sep. 30, 2022 USD ($)	Jun. 30, 2022 USD ($)	Mar. 31, 2022 USD ($)	Dec. 31, 2022 USD ($)
Significant Agreements
Realized loss on RareStone equity			$ 1,040
Loss on RareStone equity investment				$ 300
Upfront consideration	$ 8,040
Contract with customer liability revenue recognized		$ 0			$ 0
Upfront payment	7,000
Equity recorded at fair value	1,040			1,040	$ 2,440
Aggregate payment upon achievement of development and commercial milestones	$ 62,500
Shares issued for license agreement (in shares) | shares	1,077,586
License agreement
Significant Agreements
Number of performance obligations | item	2
License agreement commercial manufacturing supply discount		$ 1,286				$ 1,286
Contract with customer liability revenue recognized				$ 6,754