EX-21.1 6 rytm-20221231xex21d1.htm EX-21.1

Exhibit 21.1

Subsidiaries of Rhythm Pharmaceuticals, Inc.

Entity

Jurisdiction of Organization or Incorporation

Rhythm Pharmaceuticals Limited

Ireland

Rhythm Securities Corp.

Massachusetts

Rhythm Pharmaceuticals Netherlands, B.V.

The Netherlands

Rhythm Pharmaceuticals UK Limited

Rhythm Pharmaceuticals France SAS

Rhythm Pharmaceuticals Italy S.r.L.

Rhythm Pharmaceuticals Canada Inc.

United Kingdom

France

Italy

Canada

Rhythm Pharmaceuticals Germany GmbH

Germany

Rhythm Pharmaceuticals Spain S.L.

Spain