144 0001813798 XXXXXXXX LIVE 0001649094 Vaxcyte, Inc. 001-39323 825 INDUSTRIAL ROAD, STE. 300 SAN CARLOS CA 94070 650-837-0111 Wassil Jim Officer Common UBS Financial Services, Inc.

11 Madison Ave 4th Floor New York NY 10010

2250 130747.50 143920361 04/01/2026 NASDAQ Common 02/28/2025 RSU Vest Issuer N 783 02/28/2025 N/A Common 03/02/2025 RSU Vest Issuer N 1467 03/02/2025 N/A N James Wassil

825 INDUSTRIAL ROAD, STE. 300 SAN CARLOS CA 94070

Common 03/10/2026 7395 435438.31 04/01/2026 12/09/2025 /s/ UBS Financial Services Inc, as attorney-in-fact for James Wassil