Condensed Consolidated Statements of Stockholders’ Equity - USD ($) $ in Thousands	Total	Common Stock	Additional Paid-in Capital	Accumulated Deficit	Accumulated Other Comprehensive Gain (Loss)	Public Offering	Public Offering Common Stock	Public Offering Additional Paid-in Capital
Beginning balance (in shares) at Dec. 31, 2023		95,364,831
Beginning balance at Dec. 31, 2023	$ 1,240,468	$ 98	$ 2,164,583	$ (924,392)	$ 179
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Issuance of common stock in connection with employee incentive plans (in shares)		695,588
Issuance of common stock in connection with employee incentive plans	5,024	$ 1	5,023
Issuance of common stock from underlying pre-funded warrants in connection with follow-on public offerings (in shares)							12,695,312
Issuance of common stock from underlying pre-funded warrants in connection with follow-on public offerings						$ 816,478	$ 13	$ 816,465
Taxes paid related to the net share settlement of equity awards	(3,306)		(3,306)
Stock-based compensation expense	17,629		17,629
Other comprehensive gain (loss)	2,710				2,710
Net loss	(95,020)			(95,020)
Ending balance (in shares) at Mar. 31, 2024		108,755,731
Ending balance at Mar. 31, 2024	1,983,983	$ 112	3,000,394	(1,019,412)	2,889
Beginning balance (in shares) at Dec. 31, 2023		95,364,831
Beginning balance at Dec. 31, 2023	1,240,468	$ 98	2,164,583	(924,392)	179
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Net loss	(223,723)
Ending balance (in shares) at Jun. 30, 2024		110,575,993
Ending balance at Jun. 30, 2024	1,986,132	$ 114	3,132,318	(1,148,115)	1,815
Beginning balance (in shares) at Mar. 31, 2024		108,755,731
Beginning balance at Mar. 31, 2024	1,983,983	$ 112	3,000,394	(1,019,412)	2,889
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Issuance of common stock in connection with employee incentive plans (in shares)		317,227
Issuance of common stock in connection with employee incentive plans	4,399		4,399
Issuance of common stock from underlying pre-funded warrants in connection with follow-on public offerings (in shares)							1,503,035
Issuance of common stock from underlying pre-funded warrants in connection with follow-on public offerings						106,534	$ 2	106,532
Taxes paid related to the net share settlement of equity awards	(565)		(565)
Stock-based compensation expense	21,558		21,558
Other comprehensive gain (loss)	(1,074)				(1,074)
Net loss	(128,703)			(128,703)
Ending balance (in shares) at Jun. 30, 2024		110,575,993
Ending balance at Jun. 30, 2024	1,986,132	$ 114	3,132,318	(1,148,115)	1,815
Beginning balance (in shares) at Dec. 31, 2024		124,893,034
Beginning balance at Dec. 31, 2024	3,305,819	$ 128	4,697,883	(1,388,319)	(3,873)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Issuance of common stock in connection with employee incentive plans (in shares)		546,419
Issuance of common stock in connection with employee incentive plans	6,049	$ 1	6,048
Issuance of common stock from underlying pre-funded warrants in connection with follow-on public offerings (in shares)							3,499,959
Issuance of common stock from underlying pre-funded warrants in connection with follow-on public offerings						0	$ 3	$ (3)
Taxes paid related to the net share settlement of equity awards	(5,290)		(5,290)
Stock-based compensation expense	30,615		30,615
Other comprehensive gain (loss)	3,551				3,551
Net loss	(140,718)			(140,718)
Ending balance (in shares) at Mar. 31, 2025		128,939,412
Ending balance at Mar. 31, 2025	3,200,026	$ 132	4,729,253	(1,529,037)	(322)
Beginning balance (in shares) at Dec. 31, 2024		124,893,034
Beginning balance at Dec. 31, 2024	3,305,819	$ 128	4,697,883	(1,388,319)	(3,873)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Net loss	(307,291)
Ending balance (in shares) at Jun. 30, 2025		129,816,472
Ending balance at Jun. 30, 2025	3,071,334	$ 133	4,768,698	(1,695,610)	(1,887)
Beginning balance (in shares) at Mar. 31, 2025		128,939,412
Beginning balance at Mar. 31, 2025	3,200,026	$ 132	4,729,253	(1,529,037)	(322)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Issuance of common stock in connection with employee incentive plans (in shares)		236,375
Issuance of common stock in connection with employee incentive plans	3,235		3,235
Issuance of common stock from underlying pre-funded warrants in connection with follow-on public offerings (in shares)							640,685
Issuance of common stock from underlying pre-funded warrants in connection with follow-on public offerings						$ 1	$ 1
Taxes paid related to the net share settlement of equity awards	(717)		(717)
Stock-based compensation expense	36,927		36,927
Other comprehensive gain (loss)	(1,565)				(1,565)
Net loss	(166,573)			(166,573)
Ending balance (in shares) at Jun. 30, 2025		129,816,472
Ending balance at Jun. 30, 2025	$ 3,071,334	$ 133	$ 4,768,698	$ (1,695,610)	$ (1,887)