Condensed Consolidated Statements of Stockholders’ Equity - USD ($) $ in Thousands	Total	Common Stock	Additional Paid-in Capital	Accumulated Deficit	Accumulated Other Comprehensive Gain (Loss)	Public Offering	Public Offering Common Stock	Public Offering Additional Paid-in Capital
Beginning balance (in shares) at Dec. 31, 2023		95,364,831
Beginning balance at Dec. 31, 2023	$ 1,240,468	$ 98	$ 2,164,583	$ (924,392)	$ 179
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Issuance of common stock in connection with employee incentive plans (in shares)		695,588
Issuance of common stock in connection with employee incentive plans	5,024	$ 1	5,023
Issuance of common stock and pre-funded warrants in connection with follow-on public offering (in shares)							12,695,312
Issuance of common stock and pre-funded warrants in connection with follow-on public offering						$ 816,478	$ 13	$ 816,465
Taxes paid related to the net share settlement of equity awards	(3,306)		(3,306)
Stock-based compensation expense	17,629		17,629
Other comprehensive gain	2,710				2,710
Net loss	(95,020)			(95,020)
Ending balance (in shares) at Mar. 31, 2024		108,755,731
Ending balance at Mar. 31, 2024	1,983,983	$ 112	3,000,394	(1,019,412)	2,889
Beginning balance (in shares) at Dec. 31, 2024		124,893,034
Beginning balance at Dec. 31, 2024	3,305,819	$ 128	4,697,883	(1,388,319)	(3,873)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Issuance of common stock in connection with employee incentive plans (in shares)		546,419
Issuance of common stock in connection with employee incentive plans	6,049	$ 1	6,048
Issuance of common stock and pre-funded warrants in connection with follow-on public offering (in shares)							3,499,959
Issuance of common stock and pre-funded warrants in connection with follow-on public offering						$ 0	$ 3	$ (3)
Taxes paid related to the net share settlement of equity awards	(5,290)		(5,290)
Stock-based compensation expense	30,615		30,615
Other comprehensive gain	3,551				3,551
Net loss	(140,718)			(140,718)
Ending balance (in shares) at Mar. 31, 2025		128,939,412
Ending balance at Mar. 31, 2025	$ 3,200,026	$ 132	$ 4,729,253	$ (1,529,037)	$ (322)