Condensed Consolidated Balance Sheets - USD ($) $ in Thousands	Mar. 31, 2025	Dec. 31, 2024
Current assets:
Cash and cash equivalents	$ 346,850	$ 387,878
Short-term investments	1,324,881	1,359,330
Prepaid expenses and other current assets	44,832	40,777
Total current assets	1,716,563	1,787,985
Property and equipment, net	217,155	198,045
Operating lease right-of-use assets	87,759	72,102
Long-term investments	1,279,031	1,387,510
Restricted cash	1,319	1,317
Other assets	76,276	64,359
Total noncurrent assets	1,661,540	1,723,333
Total assets	3,378,103	3,511,318
Current liabilities:
Accounts payable	20,514	48,452
Accrued compensation	5,989	20,555
Accrued contract manufacturing expenses	38,323	36,159
Accrued expenses	26,042	29,123
Operating lease liabilities — current	6,128	5,891
Total current liabilities	96,996	140,180
Operating lease liabilities — long-term	81,081	65,319
Total liabilities	178,077	205,499
Commitments and contingencies (Note 6)
Stockholders' Equity
Preferred stock, $0.001 par value — 10,000,000 shares authorized at March 31, 2025 and December 31, 2024; no shares issued and outstanding at March 31, 2025 and December 31, 2024	0	0
Common stock, $0.001 par value — 500,000,000 shares authorized at March 31, 2025 and December 31, 2024; 128,939,412 and 124,893,034 shares issued and outstanding at March 31, 2025 and December 31, 2024, respectively	132	128
Additional paid-in capital	4,729,253	4,697,883
Accumulated other comprehensive gain	(322)	(3,873)
Accumulated deficit	(1,529,037)	(1,388,319)
Total stockholders' equity	3,200,026	3,305,819
Total liabilities and stockholders' equity	$ 3,378,103	$ 3,511,318