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Segment Reporting - Schedule of Disaggregation of Income Statement Expenses (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2022
Segment Reporting Information [Line Items]      
Research and development $ 476,644 $ 332,341 $ 169,451
Acquired manufacturing rights (Note 7) 0 75,000 22,995
General and administrative 92,902 60,700 39,810
Total operating expenses 569,546 468,041 232,256
Total other income, net 105,619 65,775 8,771
Net loss 463,927 402,266 223,485
Reportable Segment      
Segment Reporting Information [Line Items]      
Acquired manufacturing rights (Note 7) 0 75,000 22,995
General and administrative 92,902 60,700 39,810
Total operating expenses 569,546 468,041 232,256
Total other income, net 105,619 65,775 8,771
Net loss 463,927 402,266 223,485
Research and development - external costs | Reportable Segment      
Segment Reporting Information [Line Items]      
Research and development 349,510 261,984 132,418
Research and development - internal costs | Reportable Segment      
Segment Reporting Information [Line Items]      
Research and development $ 127,134 $ 70,357 $ 37,033