Funding Arrangements - Additional Information (Details) - USD ($)		1 Months Ended		12 Months Ended
	Jul. 31, 2024	Jun. 30, 2023	Apr. 30, 2021	Dec. 31, 2024	Dec. 31, 2023	Dec. 31, 2022
CARB-X Agreement
Funding Arrangement [Line Items]
Grant receivable on unreimbursed, eligible costs incurred				$ 400,000	$ 0
CARB-X Agreement | Minimum
Funding Arrangement [Line Items]
Potential funding committed by award				11,700,000
National Institutes of Health
Funding Arrangement [Line Items]
Potential funding amount of award to develop vaccine to prevent shingella infections	$ 9,500,000	$ 4,600,000	$ 500,000
National Institutes of Health | Maximum
Funding Arrangement [Line Items]
Potential funding period of award to develop vaccine to prevent shingella infections	5 years	5 years	5 years
Cost Reimbursement Sub-Award Agreement
Funding Arrangement [Line Items]
Other income (expense)				$ 1,000,000.0	$ 4,800,000	$ 1,900,000