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Condensed Statements of Cash Flows (Unaudited) - USD ($)
$ in Thousands
9 Months Ended
Sep. 30, 2021
Sep. 30, 2020
Cash flows from operating activities:    
Net loss $ (71,514) $ (68,480)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 1,341 1,073
Stock-based compensation expense 7,571 3,499
Change in fair value of redeemable convertible preferred stock warrant   179
Amortization of operating right-of-use assets 910  
Net amortization of premiums on investments 910  
Loss on disposal of fixed assets 32 32
Asset impairment charges   267
Changes in operating assets and liabilities:    
Prepaid expenses and other current assets (16,306) (1,040)
Other assets (3,030) 33
Operating lease liabilities (75)  
Accounts payable 5,601 7,330
Accrued compensation 1,791 1,076
Accrued manufacturing expenses (5,979) 18,763
Accrued expenses 8,448 1,416
Deferred rent and other long-term liabilities   (8)
Net cash used in operating activities (70,300) (35,860)
Cash flows from investing activities:    
Purchases of property and equipment (5,173) (433)
Proceeds from sale of property and equipment   50
Purchases of investments (295,279)  
Maturities of investments 58,000  
Sales of investments 30,062  
Net cash used in investing activities (212,390) (383)
Cash flows from financing activities:    
Payments of capital lease obligations   (61)
Proceeds from initial public offering, net of underwriters' commissions and discounts   267,375
Payment of issuance costs for initial public offering   (3,368)
Proceeds from issuance of redeemable convertible preferred stock, net of issuance costs   109,879
Proceeds from exercise of common stock options 1,444 454
Proceeds from issuance of common stock related to at-the-market offering, net of issuance costs 7,108  
Proceeds from issuance of common stock related to early exercised stock options   36
Proceeds from issuance of common stock under the Employee Stock Purchase Plan 490  
Net cash provided by financing activities 9,042 374,315
Effect of exchange rate changes on cash and cash equivalents 363  
Net (decrease) increase in cash, cash equivalents and restricted cash (273,285) 338,072
Cash, cash equivalents and restricted cash, beginning of period 386,200 58,976
Cash, cash equivalents and restricted cash, end of period 112,915 397,048
Supplemental disclosure of cash flow information:    
Cash paid for interest 7 7
Supplemental disclosures of non-cash investing and financing activities:    
Purchases of property and equipment recorded in accounts payable and accrued expenses 271 149
Conversion of convertible preferred stock into common stock   270,190
Issuance costs for initial public offering included in accounts payable and accrued expenses   $ 17
Stock issued for payment of accounts payable 10,000  
Deferred offering costs included in accounts payable and accrued expenses 154  
Proceeds from issuance of common stock through ATM facility not yet received $ 5,011