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Condensed Statements of Cash Flows (Unaudited) - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2021
Mar. 31, 2020
Cash flows from operating activities:    
Net loss $ (21,220) $ (27,142)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 347 384
Stock-based compensation expense 1,865 372
Change in fair value of redeemable convertible preferred stock warrant   179
Amortization of operating right-of-use assets 180  
Net amortization of premiums on investments 151  
Changes in operating assets and liabilities:    
Prepaid expenses and other current assets (557) (951)
Other assets (441) (89)
Operating lease liabilities (105)  
Accounts payable 2,185 (723)
Accrued compensation 723 (65)
Accrued manufacturing expenses 2,525 13,159
Accrued expenses 1,142 1,245
Deferred rent and other long-term liabilities   (2)
Net cash used in operating activities (13,205) (13,633)
Cash flows from investing activities:    
Purchases of property and equipment (1,246) (349)
Purchases of investments (172,145)  
Net cash used in investing activities (173,391) (349)
Cash flows from financing activities:    
Payments of capital lease obligations   (60)
Proceeds from issuance of redeemable convertible preferred stock, net of issuance costs   109,875
Proceeds from exercise of common stock options 487 49
Proceeds from issuance of common stock related to early exercised stock options   36
Payments of deferred offering costs   (103)
Net cash provided by financing activities 487 109,797
Effect of exchange rate changes on cash and cash equivalents (281)  
Net increase (decrease) in cash, cash equivalents and restricted cash (186,390) 95,815
Cash, cash equivalents and restricted cash, beginning of period 386,200 58,976
Cash, cash equivalents and restricted cash, end of period 199,810 154,791
Supplemental disclosure of cash flow information:    
Cash paid for interest   7
Supplemental disclosures of non-cash investing and financing activities:    
Purchases of property and equipment recorded in accounts payable and accrued expenses $ 1,537 35
Issuance costs for initial public offering included in accounts payable and accrued expenses   $ 142