X0306 4 2022-06-01 0 0001649094 Vaxcyte, Inc. PCVX 0001450730 Kamarck Michael E. C/O VAXCYTE, INC. 825 INDUSTRIAL ROAD, STE. 300 SAN CARLOS CA 94070 1 0 0 0 Common Stock 2022-06-01 4 A 0 3125 0.00 A 3125 D Stock Option (right to buy) 22.70 2022-06-01 4 A 0 18750 0.00 A 2032-05-31 Common Stock 18750 18750 D Represents the number of shares of Common Stock underlying restricted stock units ("RSUs"). Each RSU represents the contingent right to receive one share of the Issuer's Common Stock. The RSUs will fully vest on the earlier of June 1, 2023 or the day prior to the next annual meeting of stockholders, subject to acceleration, and subject to the Reporting Person's continuous service through such date. The shares of Common Stock subject to the option will vest monthly and fully vest on the earlier of June 1, 2023 or the day prior to the next annual meeting of stockholders, subject to acceleration, and subject to the Reporting Person's continuous service through such date. Michael E. Kamarck, by /s/ Ron A. Metzger, Attorney-in-Fact 2022-06-03