Funding Arrangement - Additional Information (Details) - USD ($) $ in Thousands	1 Months Ended		12 Months Ended
	Jun. 30, 2023	Apr. 30, 2021	Dec. 31, 2023	Dec. 31, 2022	Dec. 31, 2021	Jul. 31, 2019
Funding Arrangement [Line Items]
Grant income			$ 4,765	$ 1,931	$ 1,585
Cost Reimbursement Sub-Award Agreement
Funding Arrangement [Line Items]
Grant income			4,800	1,900	$ 1,600
CARB-X Agreement
Funding Arrangement [Line Items]
Grant receivable on unreimbursed, eligible costs incurred			$ 0	$ 1,000
CARB-X Agreement | Maximum
Funding Arrangement [Line Items]
Initial funding committed by award						$ 14,600
CARB-X Agreement | Minimum
Funding Arrangement [Line Items]
Potential funding committed by award						$ 11,700
National Institutes of Health
Funding Arrangement [Line Items]
Potential funding amount of award to develop vaccine to prevent shingella infections	$ 4,600	$ 500
National Institutes of Health | Maximum
Funding Arrangement [Line Items]
Potential funding period of award to develop vaccine to prevent shingella infections	5 years	5 years