Commitments and Contingencies - Schedule Of non-cancelable purchase Commitments Related to Raw Materials (Details) $ in Thousands	Dec. 31, 2022 USD ($)
Commitments and Contingencies Disclosure [Abstract]
2023	$ 123,099
2024	2,471
Total non-cancelable purchase commitments due to key manufacturing partners	$ 125,570

NonCancelable purchase commitments due in second year and thereafter.

No definition available.

Name:	pcvx_NoncancelablePurchaseCommitmentsDueInSecondYearAndThereafter
Namespace Prefix:	pcvx_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	instant