Balance Sheets - USD ($) $ in Thousands	Dec. 31, 2022	Dec. 31, 2021
Current assets:
Cash and cash equivalents	$ 834,657	$ 68,985
Short-term investments	96,719	176,985
Prepaid expenses and other current assets	11,179	10,378
Total current assets	942,555	256,348
Property and equipment, net	10,360	7,954
Operating lease right-of-use assets	21,288	27,958
Long-term investments	26,549	27,117
Restricted cash	871	871
Other assets	4,555	4,089
Total noncurrent assets	63,623	67,989
Total assets	1,006,178	324,337
Current liabilities:
Accounts payable	9,795	6,758
Accrued compensation	1,180	3,455
Accrued manufacturing expenses	8,265	4,440
Accrued expenses	15,375	8,787	[1]
Current operating lease liabilities	5,910	5,276
Total current liabilities	40,525	28,716
Non-current operating lease liabilities	12,031	11,507
Other liabilities	9	96
Total liabilities	52,565	40,319
Commitments and contingencies (Note 6)
Stockholders' Equity
Preferred stock, $0.001 par value - 10,000,000 authorized at December 31, 2022 and December 31, 2021; no shares issued and outstanding at December 31, 2022 and December 31, 2021	0	0
Common stock, $0.001 par value - 500,000,000 shares authorized at December 31, 2022 and December 31, 2021; 79,470,670 and 53,031,978 shares issued and outstanding at December 31, 2022 and December 31, 2021, respectively	82	56
Additional paid-in capital	1,476,018	582,844
Accumulated other comprehensive loss	(361)	(241)
Accumulated deficit	(522,126)	(298,641)
Total stockholders' equity	953,613	284,018
Total liabilities and stockholders' equity	$ 1,006,178	$ 324,337

[1] The breakout and categorizations of the 2021 total accrued expenses have been updated to conform to the 2022 presentation.