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Funding Arrangement - Additional Information (Details) - USD ($)
$ in Thousands
1 Months Ended 3 Months Ended 6 Months Ended
Apr. 30, 2021
Jul. 31, 2019
Jun. 30, 2022
Jun. 30, 2021
Jun. 30, 2022
Jun. 30, 2021
Jan. 31, 2022
Dec. 31, 2021
Aug. 04, 2021
Jul. 31, 2020
Funding Arrangement [Line Items]                    
Grant income     $ 690 $ 378 $ 850 $ 378        
Cost Reimbursement Sub-Award Agreement                    
Funding Arrangement [Line Items]                    
Funding period of award to develop universal vaccine to prevent infections caused by Group A Strep bacteria   4 years                
Potential funding amount of award to develop vaccine to prevent shingella infections $ 500                  
Grant income     700 $ 400 900 $ 400        
Cost Reimbursement Sub-Award Agreement | Maximum                    
Funding Arrangement [Line Items]                    
Initial funding committed by award   $ 1,600                
Total funding committed by award, available upon achievement of development milestones   $ 15,100                
Potential funding period of award to develop vaccine to prevent shingella infections 5 years                  
CARB-X Agreement                    
Funding Arrangement [Line Items]                    
Additional funding committed by award                 $ 3,200  
Potential funding committed by award             $ 13,900      
Grant receivable on unreimbursed, eligible costs incurred     $ 700   $ 700     $ 1,200    
CARB-X Agreement | Maximum                    
Funding Arrangement [Line Items]                    
Initial funding committed by award                   $ 2,700
Additional funding committed by award                 3,200  
Potential funding committed by award                 $ 29,700  
CARB-X Agreement | Minimum                    
Funding Arrangement [Line Items]                    
Initial funding committed by award                   $ 1,600