Funding Arrangement - Additional Information (Details) - USD ($) $ in Thousands	1 Months Ended		3 Months Ended
	Apr. 30, 2021	Jul. 31, 2019	Mar. 31, 2022	Mar. 31, 2021	Jan. 31, 2022	Dec. 31, 2021	Aug. 04, 2021	Jul. 31, 2020
Funding Arrangement [Line Items]
Grant income			$ 160
Cost Reimbursement Sub-Award Agreement
Funding Arrangement [Line Items]
Funding period of award to develop universal vaccine to prevent infections caused by Group A Strep bacteria		4 years
Potential funding amount of award to develop vaccine to prevent shingella infections	$ 500
Grant income			200	$ 0
Cost Reimbursement Sub-Award Agreement | Maximum
Funding Arrangement [Line Items]
Initial funding committed by award		$ 1,600
Total funding committed by award, available upon achievement of development milestones		$ 15,100
Potential funding period of award to develop vaccine to prevent shingella infections	5 years
CARB-X Agreement
Funding Arrangement [Line Items]
Additional funding committed by award							$ 3,200
Potential funding committed by award					$ 13,900
Grant receivable on unreimbursed, eligible costs incurred			$ 100			$ 1,200
CARB-X Agreement | Maximum
Funding Arrangement [Line Items]
Initial funding committed by award								$ 2,700
Additional funding committed by award							3,200
Potential funding committed by award							$ 29,700
CARB-X Agreement | Minimum
Funding Arrangement [Line Items]
Initial funding committed by award								$ 1,600