Expected volatility, Maximum
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Volatility Rate Maximum
Operating lease, description
Lessee Operating Lease Description
2020 Employee Stock Purchase Plan
Two Thousand Twenty Employee Stock Purchase Plan [Member]
Two thousand twenty employee stock purchase plan.
Lease expiration date
Lease Expiration Date1
Vesting period for stock options granted
Share Based Compensation Arrangement By Share Based Payment Award Award Vesting Period1
Initial funding committed by award
Initial Funding Committed By Award
Initial funding committed by award.
Segment and Geographical Information
Segment Reporting Policy Policy [Text Block]
Fair value liabilities transferred into level 3
Fair Value Measurement With Unobservable Inputs Reconciliation Liability Transfers Into Level3
Fair value liabilities transferred from level 1 to level 2
Fair Value Liabilities Level1 To Level2 Transfers Amount
Change in accounting principle, accounting standards update, early adoption [true false]
Change In Accounting Principle Accounting Standards Update Early Adoption
Commercial paper
Commercial Paper Not Included With Cash And Cash Equivalents [Member]
Operating Loss Carryforwards, Total
Net operating loss carryforwards
Operating Loss Carryforwards
Computers and Computer Software
Computers And Computer Software [Member]
Computers and computer software.
Changes in operating assets and liabilities:
Increase Decrease In Operating Liabilities [Abstract]
Preferred stock authorized
Temporary Equity Shares Authorized
Preclinical studies
Accrued Preclinical Studies Current
Accrued preclinical studies current.
Auditor Location
Unrealized losses on investments
Other Comprehensive Income Unrealized Holding Gain Loss On Securities Arising During Period Before Tax
Operating expenses:
Operating Expenses [Abstract]
Deferred rent - current
Deferred Rent Credit, Current
Asset Class
Fair Value Assets Measured On Recurring Basis Unobservable Input Reconciliation By Asset Class [Domain]
Loss from operations
Operating Income Loss
Employees acquired shares of common stock
Share Based Compensation Arrangement By Share Based Payment Award Shares Purchased For Award
Entity Emerging Growth Company
Entity Emerging Growth Company
Investments
Investment Policy [Text Block]
Income Tax Disclosure [Abstract]
Proceeds from issuance of common stock under the Employee Stock Purchase Plan
Proceeds From Stock Plans
Additional Facility
Additional Facility [Member]
Additional facility.
Common Stock Warrant
Common Stock Warrant [Member]
Common stock warrant.
Increase (Decrease) in Prepaid Expense and Other Assets, Total
Prepaid expenses and other current assets
Increase Decrease In Prepaid Deferred Expense And Other Assets
Number of reportable segments
Number Of Reportable Segments
Aggregate number of shares available for issuance
Options Available for Grant, Beginning Balance
Options Available for Grant, Ending Balance
Share Based Compensation Arrangement By Share Based Payment Award Number Of Shares Available For Grant
Funding Arrangement [Line Items]
Funding Arrangement [Line Items]
Funding arrangement.
Payments to Acquire Property, Plant, and Equipment, Total
Purchases of property and equipment
Payments To Acquire Property Plant And Equipment
Schedule Of Organization Consolidation And Presentation Of Financial Statements [Table]
Schedule Of Organization Consolidation And Presentation Of Financial Statements [Table]
Schedule of organization consolidation and presentation of financial statements.
Common stock, $0.001 par value - 500,000,000 shares authorized at December 31, 2021 and December 31, 2020;53,031,978 and 51,071,593 shares issued and outstanding at December 31, 2021 and December 31, 2020, respectively
Common Stock, Value, Issued, Ending Balance
Common Stock, Value, Issued, Beginning Balance
Common Stock, Value, Issued, Total
Common Stock Value
Entity Address State Or Province
Entity Address, State or Province
Issuance of common stock related to early exercised stock options
Stock Issued During Period Shares Issuance Of Common Stock Related To Early Exercised Stock Options
Stock issued during period shares issuance of common stock related to early exercised stock options.
Total liabilities
Liabilities
Risk-free interest rate
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Risk Free Interest Rate
Series D Redeemable Convertible Preferred Stock
Series D Redeemable Convertible Preferred Stock [Member]
Series D redeemable convertible preferred stock.
Reverse stock split
Stockholders Equity Reverse Stock Split
Receivables, Net, Current, Total
Receivables
Receivables Net Current
Accrued manufacturing expenses.
Accrued Manufacturing Expenses
Accrued manufacturing expenses
Adjustments based on tax positions related to prior years
Unrecognized Tax Benefits Increases Decreases Resulting From Prior Period Tax Positions
Class of Stock
Class Of Stock [Domain]
Options Available for Grant, forfeited
Share Based Compensation Arrangement By Share Based Payment Award Number Of Shares Available For Grant Forfeited In Period
Share-based compensation arrangement by share-based payment award number of shares available for grant forfeited in period.
Net proceeds from follow on offering
Proceeds from Issuance follow on offering
Proceeds from issuance follow on offering.
Total assets measured at fair value, Amortized Cost
Cash And Cash Equivalents And Investments Amortized Cost Basis
Cash and cash equivalents and investments amortized cost basis.
Vesting of early exercised stock options
Adjustments To Additional Paid In Capital Vesting Of Early Exercised Stock Options
Adjustments to additional paid In capital vesting of early exercised stock options.
Amount recorded with respect to the potential future payments above the initial cash cap
Guarantee Obligations Maximum Exposure
Unrealized losses on investment
OCI, Debt Securities, Available-for-Sale, Unrealized Holding Gain (Loss), before Adjustment, after Tax
Weighted-average shares outstanding used in computing net loss per share, basic and diluted
Weighted-average shares outstanding, basic and diluted
Weighted Average Number Of Share Outstanding Basic And Diluted
Redeemable Convertible Preferred Stock
Redeemable Convertible Preferred Stock [Member]
Sutro Biopharma, Inc
Sutro Biopharma Inc [Member]
Sutro Biopharma, Inc.
Options Available for Grant, exercised
Share Based Compensation Arrangement By Share Based Payment Award Number Of Shares Available For Grant Exercised In Period
Share-based compensation arrangement by share-based payment award number of shares available for grant exercised in period.
Deferred offering costs included in accounts payable and accrued expenses
Deferred Offering Costs Included In Accounts Payable And Accrued Expenses
Deferred offering costs included in accounts payable and accrued expenses.
Pre-funded warrants price per share
Prefunded Warrants Price Per Share
Prefunded warrants price per share.
License Agreement
License Agreement [Member]
License Agreement.
General and Administrative
General And Administrative Expense [Member]
Issuance of common stock to Lonza Ltd. (in shares)
Number of common stock issued
Stock Issued During Period Shares Issued For Services
Conversion of preferred stock warrant
Stock Issued During Period Shares Conversion Of Preferred Stock Warrant
Stock issued during period shares conversion of preferred stock warrant.
Weighted-Average Remaining Contractual Term (Years), Exercisable
Sharebased Compensation Arrangement By Sharebased Payment Award Options Exercisable Weighted Average Remaining Contractual Term1
Restricted Cash
Restricted Cash, Total
Schedule Of Organization Consolidation And Presentation Of Financial Statements [Line Items]
Schedule Of Organization Consolidation And Presentation Of Financial Statements [Line Items]
Schedule of organization consolidation and presentation of financial statements.
Schedule Of Related Party Transactions By Related Party [Table]
Schedule Of Related Party Transactions By Related Party [Table]
City Area Code
City Area Code
Cash and cash equivalents, Amortized Cost
Cash And Cash Equivalents Amortized Cost
Cash and cash equivalents amortized cost.
Summary of Estimated Fair Value of Employee Stock Options
Schedule Of Share Based Payment Award Stock Options Valuation Assumptions Table [Text Block]
Total
Deferred Tax Assets Gross
U.S. Treasury Securities
U S Treasury Securities [Member]
Accounting standard update adopted
Change in Accounting Principle, Accounting Standards Update, Adopted [true false]
Weighted-Average Exercise Price Per Share, Options forfeited
Share Based Compensation Arrangements By Share Based Payment Award Options Forfeitures In Period Weighted Average Exercise Price
Commitments and contingencies (Note 6)
Commitments And Contingencies
Series C Redeemable Convertible Stock
Series C Redeemable Convertible Preferred Stock
Series C Redeemable Convertible Preferred Stock [Member]
Series C redeemable convertible preferred stock.
Schedule of Potentially Dilutive Securities Excluded From Computation of Diluted Net Loss Per Share
Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Text Block]
Research credit carryforwards
Income Tax Reconciliation Tax Credits Research
Common stock shares sold
Shares issued
Issuance of common stock upon initial public offering or at-the-market offering, net of issuance costs (in shares)
Total
Investments, Fair Value
Available For Sale Securities Debt Securities
Redeemable Convertible Preferred Stock Warrant
Redeemable Convertible Preferred Stock Warrant [Member]
Redeemable convertible preferred stock warrant.
Basis of Presentation
Basis Of Accounting Policy Policy [Text Block]
Cash
Cash [Member]
Issuance of common stock under Employee Stock Purchase Plan (in shares)
Stock Issued During Period Shares Employee Stock Purchase Plans
Cash, cash equivalents and restricted cash
Cash, cash equivalents and restricted cash, end of period
Cash, cash equivalents and restricted cash, beginning of period
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents
Warrant to purchase shares of stock
Class Of Warrant Or Right Number Of Securities Called By Each Warrant Or Right
Related Party
Related Party [Domain]
Accounting standard update material impact
Change in Accounting Principle, Accounting Standards Update, Immaterial Effect [true false]
Common stock price per share
Shares Issued Price Per Share upon follow on offering
Shares issued price per share upon follow on offering.
Cash and cash equivalents, Gross Unrealized Losses
Cash And Cash Equivalents Gross Unrealized Loss Before Tax
Cash and cash equivalents gross unrealized loss before tax.
Income Statement [Abstract]
Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table]
Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table]
Other income (expense), net:
Other Nonoperating Income Expense [Abstract]
Total noncurrent assets
Total noncurrent assets
Assets Noncurrent
Grant income
Grant Income
Grant income.
Net cash used in investing activities
Net Cash Provided By Used In Investing Activities
Purchases of property and equipment recorded in accounts payable and accrued expenses
Capital Expenditures Incurred But Not Yet Paid
Tax Credit Carryforward
Tax Credit Carryforward [Axis]
Percentage of outstanding number of shares
Share Based Compensation Arrangement By Share Based Payment Award Percentage Of Outstanding Stock Maximum
Tax credit carry forwards expiration year
Tax Credit Carryforward Expiration Year
Tax credit carryforward expiration year.
Tax Credit Carryforward, Name
Tax Credit Carryforward Name [Domain]
Accrued compensation
Employee-related Liabilities, Current
Employee-related Liabilities, Current, Total
Summary of Estimated Fair Value of Shares Under Employee Stock Purchase Plan
Schedule Of Share Based Payment Award Employee Stock Purchase Plan Valuation Assumptions Table [Text Block]
General and Administrative Expense, Total
General and administrative
General And Administrative Expense
Property, Plant and Equipment, Net, Ending Balance
Property, Plant and Equipment, Net, Beginning Balance
Property and equipment, net
Property and equipment, net
Property Plant And Equipment Net
Common Stock, Shares, Issued, Total
Common stock, shares owned
Common stock, shares issued
Common Stock Shares Issued
Deferred rent - long-term
Deferred Rent Credit, Noncurrent
Statement Of Income And Comprehensive Income [Abstract]
Total deferred tax liabilities
Total deferred tax liabilities
Total deferred tax liabilities
Deferred Tax Liabilities, Gross
Asset backed securities
Investments, Amortized Cost
Available For Sale Debt Securities Amortized Cost Basis
Operating lease, ROU assets
ROU assets
Operating lease right-of-use assets
Security Exchange Name
Security Exchange Name
Statistical Measurement
Range [Member]
Furniture and Equipment
Furniture And Fixtures [Member]
Net Income (Loss) Available to Common Stockholders, Basic, Total
Net loss (in thousands)
Net Income Loss Available To Common Stockholders Basic
Operating lease liabilities
Increase Decrease In Operating Lease Liabilities
Increase decrease in operating lease liabilities.
Other liabilities
Other Liabilities, Noncurrent
Other Liabilities, Noncurrent, Total
Fair value assets transferred out of level 3
Fair Value Measurement With Unobservable Inputs Reconciliation Recurring Basis Asset Transfers Out Of Level3
ASU 2019-12
Accounting Standards Update 2019-12 [Member]
Cash and cash equivalents, Fair Value
Cash And Cash Equivalents Fair Value Disclosure
Palo Alto
Palo Alto [Member]
Palo alto.
Subsequent Event Type
Subsequent Event Type [Domain]
Document Period End Date
Document Period End Date
Restricted cash
Restricted Cash Noncurrent
Income Statement Location
Income Statement Location [Axis]
Accrued expenses (including related party accrual of $0 and $677 as of December 31, 2021 and December 31, 2020, respectively)
Total
Accrued Liabilities Current
Accrued compensation
Increase Decrease In Accrued Compensation
Increase decrease in accrued compensation.
Expenses related to agreement
Related Party Transaction Expenses From Transactions With Related Party
Related Party Transaction
Related Party Transaction [Axis]
Loss Contingencies [Table]
Loss Contingencies [Table]
Common stock, shares authorized
Common Stock Shares Authorized
Percentage of royalty payment on annual net sales of vaccine products for human health
Percentage Of Royalty Payment On Annual Net Sales Of Vaccine Products For Human Health
Percentage of royalty payment on annual net sales of vaccine products for human health.
Use of Estimates
Use Of Estimates
Operating lease liabilities — current
Operating Lease Liability Current
Net amortization of premiums on investments
Accretion (Amortization) of Discounts and Premiums, Investments
Related Party
Related Party Transactions By Related Party [Axis]
Supplemental disclosure of cash flow information:
Supplemental Cash Flow Information [Abstract]
Underwriters' option to purchase additional shares
Shares issued upon follow on offering full exercise of underwriters option to purchase additional shares.
Shares issued upon follow on offering full exercise of underwriters option to purchase additional shares.
Class of Stock
Statement Class Of Stock [Axis]
Underwriting discounts and commissions
Payments Of Underwriting Discounts And Commissions
Payments of underwriting discounts and commissions.
Adjustments to reconcile net loss to net cash used in operating activities:
Adjustments To Reconcile Net Income Loss To Cash Provided By Used In Operating Activities [Abstract]
Antidilutive securities excluded from computation of diluted net loss per share
Antidilutive Securities Excluded From Computation Of Earnings Per Share Amount
Number of finance lease
Number Of Finance Lease
Number of finance lease.
Options Available for Grant, granted
Share Based Compensation Arrangement By Share Based Payment Award Number Of Shares Available For Grant Granted In Period
Share-based compensation arrangement by share-based payment award number of shares available for grant granted in period.
Warrant liability write-off
Adjustments To Additional Paid In Capital Warrant Liability Write Off
Adjustments to additional paid in capital warrant liability write off.
Lease incentives
Lease Payment Receivable Noncurrent
Gain (Loss) on Disposition of Assets, Total
Loss on disposal of assets
Gain Loss On Disposition Of Assets1
Cash paid for interest
Interest Paid Net
Maximum commission percentage of gross proceeds from common stock sold
Maximum Commission Percentage Of Gross Proceeds From Common Stock Sold
Maximum commission percentage of gross proceeds from common stock sold.
Schedule of Information Related to ROU Assets and Lease Liabilities
Schedule Of Information Related To Right Of Use Assets And Lease Liabilities Table [Text Block]
Schedule of information related to right-of-use assets and lease liabilities.
Total
Effective Income Tax Rate Continuing Operations
Entity Address Address Line2
Entity Address, Address Line Two
Current Fiscal Year End Date
Current Fiscal Year End Date
Net (decrease) increase in cash, cash equivalents and restricted cash
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Period Increase Decrease Including Exchange Rate Effect
Increase (Decrease) in Other Operating Assets, Total
Other assets
Increase Decrease In Other Operating Assets
Proceeds from issuance of common stock related to early exercised stock options
Proceeds From Issuance Of Common Stock Related To Early Exercised Stock Options
Proceeds from issuance of common stock related to early exercised stock options.
Operating lease, existence of option to renewal
Lessee Operating Lease Existence Of Option To Extend
Office
Building [Member]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis Valuation Techniques [Table]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis Valuation Techniques [Table]
Counterparty Name
Counterparty Name [Axis]
Assets
Assets [Abstract]
Preferred stock converted into common stock
Conversion of preferred stock (in shares)
Stock Issued During Period Shares Conversion Of Convertible Securities
Conversion of common stock warrant
Stock Issued During Period Shares Conversion Of Common Stock Warrant
Stock issued during period shares conversion of common stock warrant.
Assets:
Assets Fair Value Disclosure [Abstract]
Fair value assets transferred into level 3
Fair Value Measurement With Unobservable Inputs Reconciliation Recurring Basis Asset Transfers Into Level3
2021
2021
Lessee Operating Lease Liability Payments Due Next Twelve Months
Fair value assets transferred from level 2 to level 1
Fair Value Assets Level2 To Level1 Transfers Amount
Accounts payable
Accounts Payable, Current
Accounts Payable, Current, Total
U.S. Government Agency Securities
U S Government Agencies Debt Securities [Member]
Common stock, par value per share
Common stock, par value
Common Stock Par Or Stated Value Per Share
Funding Arrangement [Table]
Funding Arrangement [Table]
Funding arrangement.
Section 59(e) Capitalized expenses
Deferred Tax Assets In Process Research And Development
Related Party Transaction, Due from (to) Related Party, Total
Accrued expenses payable
Related Party Transaction Due From To Related Party
Additions based on tax positions related to current year
Unrecognized Tax Benefits Increases Resulting From Current Period Tax Positions
State
State And Local Jurisdiction [Member]
Beginning balance, shares
Ending balance, shares
Shares Outstanding
Operating lease, extended term
Lessee Operating Lease Extended Lease Term
Lessee operating lease extended lease term.
ATM Sales Agreement
A T M Sales Agreement [Member]
ATM sales agreement.
Additional Paid in Capital, Common Stock, Ending Balance
Additional Paid in Capital, Common Stock, Beginning Balance
Additional paid-in capital
Additional Paid In Capital Common Stock
Research and Development
Research And Development Expense Policy
Document Type
Document Type
Federal
Domestic Country [Member]
Effective Income Tax Rate Continuing Operations Tax Rate Reconciliation [Abstract]
Preferred Stock, Value, Issued, Ending Balance
Preferred Stock, Value, Issued, Beginning Balance
Preferred Stock, Value, Issued, Total
Preferred stock, $0.001 par value — 10,000,000 authorized at December 31, 2021 and December 31, 2020; no shares issued and outstanding at December 31, 2021 and December 31, 2020
Preferred Stock Value
Operating lease liabilities — long-term
Operating Lease Liability Noncurrent
Payments in equity, amount
Development And Manufacturing Services Agreement Payments In Equity
Development and manufacturing services agreement payments in equity.
Schedule of Accrued Expenses
Schedule Of Accrued Liabilities Table [Text Block]
Total current assets
Assets Current
Percentage of provisions subject to stockholders
Percentage Of Provisions Subject To Stockholders
Percentage of provisions subject to stockholders.
Stock-Based Compensation Expense
Share Based Compensation Option And Incentive Plans Policy
Early exercised stock options
Early Exercised Stock Options
Early exercised stock options.
Options Issued and Outstanding
Employee Stock Option [Member]
Supply Agreement
Supply Agreement [Member]
Supply Agreement.
Weighted-Average Remaining Contractual Term (Years)
Sharebased Compensation Arrangement By Sharebased Payment Award Options Outstanding Weighted Average Remaining Contractual Term2
Preferred Stock Warrant
Preferred Stock Warrant [Member]
Preferred stock warrant.
Supplemental disclosures of non-cash investing and financing activities:
Cash Flow Noncash Investing And Financing Activities Disclosure [Abstract]
Total funding committed by award, available upon achievement of development milestones
Funding Committed By Award Available Upon Achievement Of Development Milestones
Funding committed by award, available upon achievement of development milestones.
Jefferies LLC
Jefferies Limited Liability Company [Member]
Jefferies limited liability company.
Earnings Per Share, Basic and Diluted, Total
Net loss per share, basic and diluted
Earnings Per Share Basic And Diluted
Total assets measured at fair value, Fair Value
Cash And Cash Equivalents And Investments
Cash and cash equivalents and investments.
Leases [Abstract]
Antidilutive Securities
Antidilutive Securities Excluded From Computation Of Earnings Per Share By Antidilutive Securities [Axis]
2014 Equity Incentive Plan
Two Thousand Fourteen Equity Incentive Plan [Member]
Two thousand fourteen equity incentive plan.
Loss Contingencies [Line Items]
Loss Contingencies [Line Items]
Series B Redeemable Convertible Preferred Stock
Series B Redeemable Convertible Preferred Stock [Member]
Series B redeemable convertible preferred stock.
Aggregate Intrinsic Value, Vested and expected to vest
Share Based Compensation Arrangement By Share Based Payment Award Options Vested And Expected To Vest Outstanding Aggregate Intrinsic Value
Deferred Tax Assets, Operating Loss Carryforwards, Total
Net operating losses
Deferred Tax Assets Operating Loss Carryforwards
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis Valuation Techniques [Line Items]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis Valuation Techniques [Line Items]
Stock issued for payment of accounts payable
Stock Issued1
Common Stock, Shares, Outstanding, Ending Balance
Common Stock, Shares, Outstanding, Beginning Balance
Common stock, shares outstanding
Common Stock Shares Outstanding
Plan Name
Plan Name [Axis]
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Ending Balance
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Beginning Balance
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Total
Less: accumulated depreciation and amortization
Accumulated Depreciation Depletion And Amortization Property Plant And Equipment
Number of Options, forfeited
Share Based Compensation Arrangement By Share Based Payment Award Options Forfeitures In Period
Total operating expenses
Operating Expenses
Deferred tax assets:
IPO
Initial Public Offering
I P O [Member]
Issuance costs
Adjustments To Additional Paid In Capital Stock Issued Issuance Costs
Investments, Gross Unrealized Losses
Available For Sale Debt Securities Accumulated Gross Unrealized Loss Before Tax
Weighted-Average Exercise Price Per Share, Beginning Balance
Weighted-Average Exercise Price Per Share, Ending Balance
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Weighted Average Exercise Price
Cash flows from operating activities:
Net Cash Provided By Used In Operating Activities [Abstract]
Schedule of Maturities of Lease Liabilities
Lessee Operating Lease Liability Maturity Table [Text Block]
Warrant purchase price per share
Class Of Warrant Or Right Exercise Price Of Warrants Or Rights1
Investments, Gross Unrealized Gains
Available For Sale Debt Securities Accumulated Gross Unrealized Gain Before Tax
Earnings Per Share [Abstract]
Percentage of fair value per share on the grant date
Percentage Of Fair Value Per Share On The Grant Date
Percentage of fair value per share on the grant date.
Equity payment, upper limit
Threshold Limit On Equity Payments
Threshold limit on equity payments.
Aggregate gross proceeds from issuance of common stock
Gross Proceeds From Issuance Of Common Stock
Gross proceeds from issuance of common stock.
2023 and 2022
Lessee Operating Lease Liability Payments Due Year Two
Net loss
Net Loss
Net Income Loss
Reconciliation of Effective Tax Rate
Schedule Of Effective Income Tax Rate Reconciliation Table [Text Block]
Concentration of Credit Risk and Other Risks and Uncertainties
Concentration Risk Credit Risk
Weighted-average discount rate
Operating Lease Weighted Average Discount Rate Percent
Research and Development
Research And Development Expense [Member]
Income Tax Disclosure [Line Items]
Income Tax Disclosure [Line Items]
Income tax disclosure.
Document Fiscal Period Focus
Document Fiscal Period Focus
Issuance of preferred stock
Temporary Equity Stock Issued During Period Value New Issues
Accounting Policies [Abstract]
Accumulated other comprehensive loss
Accumulated Other Comprehensive Income (Loss), Net of Tax
Accumulated Other Comprehensive Income (Loss), Net of Tax, Total
Entity Address Address Line1
Entity Address, Address Line One
Intrinsic value of the stock options exercised
Share Based Compensation Arrangement By Share Based Payment Award Options Exercises In Period Total Intrinsic Value
Number of shares outstanding
Number of Options, Beginning Balance
Number of Options, Ending Balance
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Number
Grant receivable on unreimbursed, eligible costs incurred
Grants Receivable
Number of renewal options
Number Of Renewal Options
Number of renewal options.
Asset backed securities
Asset-backed Securities [Member]
Issuance of preferred stock, net of issuance cost (in shares)
Temporary Equity Stock Issued During Period Shares New Issues
Temporary equity stock issued during period shares new issues.
Total current liabilities
Liabilities, Current
Payments in equity, percentage
Development And Manufacturing Services Agreement Equity Payments Percentage
Development and manufacturing services agreement equity payments percentage.
Net Income (Loss), Including Portion Attributable to Noncontrolling Interest, Total
Net loss
Profit Loss
Commercial Paper
Commercial Paper [Member]
Entity Address Postal Zip Code
Entity Address, Postal Zip Code
Expense on issuance of redeemable convertible preferred stock warrant
Expense On Issuance Of Redeemable Convertible Preferred Stock Warrant
Expense on issuance of redeemable convertible preferred stock warrant.
Potential funding amount of award to develop vaccine to prevent shingella infections
Potential Funding Amount Of Award To Develop Vaccine To Prevent Infections
Potential funding amount of award to develop vaccine to prevent infections.
Risk-free interest rate, Maximum
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Risk Free Interest Rate Maximum
Aggregate Intrinsic Value
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Intrinsic Value
License Amendment A2
License Amendment A Two [Member]
License Amendment A Two.
Total future undiscounted lease payments
Lessee Operating Lease Liability Payments Due
Subsequent Event [Table]
Product and Service
Products And Services [Domain]
Beginning balance
Ending balance
Temporary Equity Carrying Amount Attributable To Parent
Sales of investments
Proceeds from Sale of Debt Securities, Available-for-sale
Net proceeds from initial public offering
Proceeds From Issuance Initial Public Offering
Options Available for Grant, Additional shares authorized
Share Based Compensation Arrangement By Share Based Payment Award Number Of Additional Shares Authorized
Collaborative Arrangement and Arrangement Other than Collaborative
Arrangements And Nonarrangement Transactions [Member]
Operating lease, commencement date
Lessee Operating Lease Commencement Date
Lessee operating lease commencement date.
Net cash used in operating activities
Net Cash Provided By Used In Operating Activities
Common stock, dividends, per share, declared
Common Stock Dividends Per Share Declared
Lonza DMSA
Lonza Limited [Member]
Lonza limited.
Equity Components
Statement Equity Components [Axis]
Current assets:
Assets Current [Abstract]
Entity Registrant Name
Entity Registrant Name
Other comprehensive loss:
Other Comprehensive Income Loss Net Of Tax Portion Attributable To Parent [Abstract]
Aggregate offering price
Sale Of Common Stock Authorized Amount
Sale of common stock authorized amount.
Common Stock
Stockholders Equity Note Disclosure [Text Block]
Funding Arrangement
Funding Arrangement [Text Block]
Funding arrangement.
Entity Interactive Data Current
Entity Interactive Data Current
Pneumococcal Conjugate Vaccine
Pneumococcal Conjugate Vaccine [Member]
Pneumococcal conjugate vaccine.
Entity Address City Or Town
Entity Address, City or Town
Expected volatility, Minimum
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Volatility Rate Minimum
Effective Income Tax Rate Reconciliation, Tax Credit, Percent, Total
Credits
Effective Income Tax Rate Reconciliation Tax Credits
Balance Sheet Details
Supplemental Balance Sheet Disclosures [Text Block]
Expected term (in years)
Sharebased Compensation Arrangement By Sharebased Payment Award Fair Value Assumptions Expected Term1
Trading Symbol
Trading Symbol
Related Party Transactions
Related Party Transactions Disclosure [Text Block]
Cash flows from investing activities:
Net Cash Provided By Used In Investing Activities [Abstract]
2020 Plan and 2014 Plan
Two Thousand Twenty Equity Incentive Plan And Two Thousand Fourteen Equity Incentive Plan [Member]
Two thousand twenty equity incentive plan and two thousand fourteen equity incentive plan.
Less: Imputed interest
Lessee Operating Lease Liability Undiscounted Excess Amount
2014 Plan, 2020 Plan and 2020 ESPP
Two Thousand Fourteen Equity Incentive Plan And Two Thousand Twenty Equity Incentive Plan And Two Thousand Twenty Employee Stock Purchase Plan [Member]
Two thousand fourteen equity incentive plan and two thousand twenty equity incentive plan and two thousand twenty employee stock purchase plan.
Local Phone Number
Local Phone Number
ASU 2016-02
Accounting Standards Update201602 [Member]
Number of securities
Number Of Securities
Number of securities.
Total stockholders' equity
Beginning balance
Ending balance
Stockholders Equity
Subsequent Event Type
Subsequent Event Type [Axis]
Uncertain tax benefits
Balance at the beginning of the year
Balance at end of year
Unrecognized Tax Benefits
Market offering
Market Offering [Member]
Market offering.
Cash paid for operating lease liabilities
Operating Lease Payments
Comprehensive Loss
Comprehensive Income Policy Policy [Text Block]
Preferred Stock, Shares Issued, Total
Preferred stock, shares issued
Preferred Stock Shares Issued
Statistical Measurement
Range [Axis]
Entity Small Business
Entity Small Business
Purchases of investments
Payments to Acquire Debt Securities, Available-for-sale
Preferred Stock, Shares Outstanding, Ending Balance
Preferred Stock, Shares Outstanding, Beginning Balance
Preferred stock, shares outstanding
Preferred Stock Shares Outstanding
Deferred Tax Assets, Tax Credit Carryforwards, Total
Credits
Deferred Tax Assets Tax Credit Carryforwards
Organization Consolidation And Presentation Of Financial Statements [Abstract]
Leases
Lessee Leases Policy [Text Block]
Operating lease, rent commencement date
Lessee Operating Lease Rent Commencement Date
Lessee, operating lease, rent commencement date.
Fair Value Hierarchy and NAV
Fair Value Measurements Fair Value Hierarchy [Domain]
APIC, Share-based Payment Arrangement, Increase for Cost Recognition, Total
Stock-based compensation expense
Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value
Underwritten Public Offering
Underwriter
Over-Allotment Option [Member]
Components of Deferred Tax Assets
Schedule Of Deferred Tax Assets And Liabilities Table [Text Block]
Accrued Liabilities Current [Abstract]
Impairment of Long-Lived Assets
Impairment Or Disposal Of Long Lived Assets Policy [Text Block]
Research
Research [Member]
Common stock, voting rights
Common Stock Voting Rights
Estimated useful lives of assets
Property, Plant and Equipment, Useful Life
Operating loss carry forwards expiration year
Operating Loss Carry Forwards Expiration Year
Operating loss carry forwards expiration year
Balance Sheet Location
Balance Sheet Location [Axis]
Equity incentive plan, shares issued
Share Based Compensation Arrangement By Share Based Payment Award Shares Issued In Period
Fair Value Measurements
Fair Value Measurement Policy Policy [Text Block]
Change in fair value of redeemable convertible preferred stock warrant
Fair Value Adjustment Of Warrants
Percentage of royalty payment on net sales of vaccine compositions for animal health
Percentage Of Royalty Payment On Net Sales Of Vaccine Compositions For Animal Health
Percentage of royalty payment on net sales of vaccine compositions for animal health.
Reconciliation Of Unrecognized Tax Benefits Excluding Amounts Pertaining To Examined Tax Returns Roll Forward
Purchase period
Purchase Period
Purchase period.
New Corporate Headquarters Facility
New Corporate Headquarters Facility [Member]
New Corporate Headquarters Facility.
Schedule of Financial Instruments Measured at Fair Value on Recurring Basis
Fair Value Assets Measured On Recurring Basis [Text Block]
Deferred Offering Costs
Deferred Charges Policy [Text Block]
Weighted-Average Exercise Price Per Share, Options granted
Share Based Compensation Arrangements By Share Based Payment Award Options Grants In Period Weighted Average Exercise Price
Sale of Stock
Sale Of Stock Name Of Transaction [Domain]
Offering period
Offering Period
Offering period.
Equity [Abstract]
Proceeds from sales of property and equipment
Proceeds from Sale of Property, Plant, and Equipment, Total
Proceeds From Sale Of Property Plant And Equipment
Related Party Transaction [Line Items]
Related Party Transaction [Line Items]
Funding period of award to develop universal vaccine to prevent infections caused by Group A Strep bacteria
Funding Period Of Award To Develop Universal Vaccine To Prevent Infections
Funding period of award to develop universal vaccine to prevent infections.
Payments of capital lease obligations
Payments Of Capital Lease Obligations
Payments of capital lease obligations.
Plan Name
Plan Name [Domain]
Temporary Equity By Class Of Stock [Table]
Temporary Equity By Class Of Stock [Table]
Lessee Lease Description [Table]
Lessee Lease Description [Table]
Class Of Stock [Line Items]
Class Of Stock [Line Items]
Income Tax Authority
Income Tax Authority [Axis]
Conversion of preferred stock (in shares)
Temporary Equity Conversion Of Preferred Stock Shares
Temporary equity conversion of preferred stock shares.
Operating lease, agreement term
Lessee Operating Lease Term Of Contract
Issuance of common stock upon initial public offering or at-the-market offering, net of issuance costs
Stock Issued During Period Value New Issues
California
C A
Interest Expense, Total
Interest expense
Interest Expense
Due to Related Parties, Current, Total
Related party accrual
Due To Related Parties Current
Issuance of common stock to LonzaLtd.
Stock Issued During Period Value Issued For Services
Foreign currency transaction gains (losses)
Foreign Currency Transaction Gain (Loss), before Tax, Total
Foreign Currency Transaction Gain Loss Before Tax
Share-based Payment Arrangement, Noncash Expense, Total
Stock-based compensation expense
Share Based Compensation
Prepaid expenses and other current assets
Prepaid Expense And Other Assets Current
Summary of Activity Under Stock Option Plans
Schedule Of Share Based Compensation Stock Options Activity Table [Text Block]
Long-Lived Tangible Asset
Property Plant And Equipment Type [Domain]
Related Party Transactions [Abstract]
Accrued manufacturing expenses
Deferred Tax Assets Tax Accrued Manufacturing Expenses
Deferred tax assets tax accrued manufacturing expenses.
Deferred offering costs
Deferred Offering Costs
Other
Effective Income Tax Rate Reconciliation Other Adjustments
Warrant exercisable and vests immediately and expires date
Class Of Warrant Or Righst Date From Which Warrants Or Rights Exercisable
Number of Options, Exercisable
Share Based Compensation Arrangement By Share Based Payment Award Options Exercisable Number
Net cash provided by financing activities
Net Cash Provided By Used In Financing Activities
Percentage of payroll deductions of eligible compensation
Share Based Compensation Arrangement By Share Based Payment Award Maximum Employee Subscription Rate
Commitments And Contingencies Disclosure [Abstract]
Total assets
Assets
Level 2
Fair Value Inputs Level2 [Member]
Reconciliation of Unrecognized Tax Benefit
Summary Of Income Tax Contingencies [Text Block]
Leases
Number of Options, exercised
Exercise of stock options (in shares)
Stock Issued During Period Shares Stock Options Exercised
Statement [Line Items]
Statement [Line Items]
Total liabilities, redeemable convertible preferred stock and stockholders' equity
Liabilities, Redeemable Convertible Preferred Stock and Stockholders' Equity
Liabilities And Stockholders Equity
Balance Sheet Location
Balance Sheet Location [Domain]
Property Plant And Equipment [Abstract]
Statement Of Cash Flows [Abstract]
Additional Paid-in Capital
Additional Paid In Capital [Member]
Security12b Title
Title of 12(b) Security
Comprehensive Loss
Comprehensive Income Net Of Tax
Effect of exchange rate changes on cash and cash equivalents
Effect Of Exchange Rate On Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents
Level 3
Fair Value Inputs Level3 [Member]
Entity Well-known Seasoned Issuer
Exercise price expire in years form the date of grant
Exercise Price Expire In Years Form The Date Of Grant
Exercise price expire in years form the date of grant.
Warrant exercised
Class Of Warrant Or Right Number Of Securities Called By Each Warrant Or Right Exercised
Class of warrant or right number of securities called by each warrant or right exercised.
Award Type
Share Based Compensation Arrangements By Share Based Payment Award Award Type And Plan Name [Domain]
Vesting percentage for stock options granted
Sharebased Compensation Arrangement By Sharebased Payment Award Award Vesting Rights Percentage
Fair Value Hierarchy and NAV
Fair Value By Fair Value Hierarchy Level [Axis]
Term of plan
Sharebased Compensation Arrangement By Sharebased Payment Award Expiration Period
Interest income
Investment Income Interest
Exercise of stock options (in shares)
Number Of Options Exercised Excludes Options Exercised From NPLN
Number of options exercised, excludes options exercised from NPLN.
Schedule of Property and Equipment, Net
Property Plant And Equipment [Text Block]
IPO-related costs
Initial Public Offering Related Cost
Initial public offering related cost.
Level 1
Fair Value Inputs Level1 [Member]
Capital Leases — Lab Equipment
Capital Leases Lab Equipment [Member]
Capital leases — lab equipment.
2025
Lessee Operating Lease Liability Payments Due Year Four
Net deferred taxes
Deferred Tax Assets, Net
Accrued manufacturing expenses
Increase Decrease In Accrued Manufacturing Expenses
Increase decrease in accrued manufacturing expenses.
Change in valuation allowance
Effective Income Tax Rate Reconciliation Change In Deferred Tax Assets Valuation Allowance
Corporate Debt
Corporate Debt Securities [Member]
Weighted-Average Exercise Price Per Share, Vested and expected to vest
Share Based Compensation Arrangement By Share Based Payment Award Options Vested And Expected To Vest Outstanding Weighted Average Exercise Price
Options granted
Number of Options, granted
Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Gross
Entity Current Reporting Status
Entity Current Reporting Status
2022
2022
Lessee Operating Lease Liability Payments Due Next Twelve Months Net of Lease Incentives
Lessee operating lease liability payments due next twelve months net of lease incentives.
Entity Voluntary Filers
Entity Voluntary Filers
Risk-free interest rate, Minimum
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Risk Free Interest Rate Minimum
Shares issued
Stock Issued During Period, Shares of follow on offering
Stock issued during period, shares of follow on offering.
Money Market Funds
Money Market Funds [Member]
Documents Incorporated By Reference [Text Block]
Documents Incorporated by Reference
Global target revenue
Global Target Revenue
Global target revenue.
Operating lease, option to renewal, description
Lessee Operating Lease Option To Extend
Performance-based Awards
Performance Shares [Member]
Net Loss Per Share
Earnings Per Share Policy [Text Block]
Payments of deferred offering costs
Payment Of Deferred Offering Costs
Payment of deferred offering costs.
Realized gains on marketable securities
Marketable Securities, Realized Gain (Loss), Total
Marketable Securities Realized Gain Loss
Accumulated Other Comprehensive Loss
Accumulated Other Comprehensive Income [Member]
Auditor Firm ID
Other Liabilities
Other Noncurrent Liabilities [Member]
Income Statement Location
Income Statement Location [Domain]
Proceeds from issuance of common stock through ATM facility not yet received
Proceeds From Issuance Of Common Stock Not Yet Received
Proceeds from issuance of common stock not yet received.
Schedule of Common Stock Shares Reserved for Future Issuance
Schedule Of Common Stock Shares Reserved For Future Issuance Table [Text Block]
Schedule of common stock shares reserved for future issuance.
Auditor Name
Preferred stock, shares authorized
Preferred Stock Shares Authorized
Weighted-Average Exercise Price Per Share, Exercisable
Share Based Compensation Arrangement By Share Based Payment Award Options Exercisable Weighted Average Exercise Price
Increase (Decrease) in Accrued Liabilities, Total
Accrued expenses
Increase Decrease In Accrued Liabilities
Stock options granted term
Stock Options Granted Term
Stock options granted term.
Unrecognized Tax Benefits, Income Tax Penalties and Interest Expense, Total
Interest or penalties recognized for the period
Unrecognized Tax Benefits Income Tax Penalties And Interest Expense
Minimum
Minimum [Member]
Minimum [Member]
Weighted-Average Remaining Contractual Term (Years), Vested and expected to vest
Sharebased Compensation Arrangement By Sharebased Payment Award Options Vested And Expected To Vest Outstanding Weighted Average Remaining Contractual Term1
Measurement Frequency
Fair Value Measurement Frequency [Domain]
Percentage of defer payments agreed for completion
Percentage Of Payments Completion Agreed To Defer
Percentage of payments completion agreed to defer.
Exercise of stock options
Stock Issued During Period Value Stock Options Exercised
Due in less than one year
Available For Sale Securities Debt Maturities Within One Year Fair Value
Other Assets
Other Noncurrent Assets [Member]
New Accounting Pronouncements Or Change In Accounting Principle [Table]
New Accounting Pronouncements Or Change In Accounting Principle [Table]
Company Organization and Nature of Business
Organization Consolidation And Presentation Of Financial Statements Disclosure [Text Block]
Conversion of preferred stock
Temporary Equity Conversion Of Preferred Stock Value
Temporary equity conversion of preferred stock value.
Document Annual Report
Document Annual Report
Asset Impairment Charges, Total
Asset impairment charges
Asset Impairment Charges
Fair Value Assumptions
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions And Methodology [Abstract]
Change in fair value of redeemable convertible preferred stock tranche liabilities
Change In Fair Value Of Redeemable Convertible Preferred Stock Tranche Liabilities
Change in fair value of redeemable convertible preferred stock tranche liabilities.
Deferred Tax Assets, Valuation Allowance, Total
Valuation allowance
Deferred Tax Assets Valuation Allowance
Cost Reimbursement Sub-Award Agreement
Cost Reimbursement Sub Award Agreement [Member]
Cost reimbursement sub-award agreement.
Deffered Tax Assets Lease Liability
Lease Liability
Lease liability.
Cash flows from financing activities:
Net Cash Provided By Used In Financing Activities [Abstract]
Share-based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount, Total
Unrecognized stock-based compensation expense
Employee Service Share Based Compensation Nonvested Awards Total Compensation Cost Not Yet Recognized
Total assets measured at fair value, Gross Unrealized Gains
Cash And Cash Equivalents And Investments Gross Unrealized Gain Before Tax
Cash and cash equivalents and investments gross unrealized gain before tax.
Total assets measured at fair value, Gross Unrealized Losses
Cash And Cash Equivalents And Investments Gross Unrealized Loss Before Tax
Cash and cash equivalents and investments gross unrealized loss before tax.
Foreign Currency Transactions
Foreign Currency Transactions And Translations Policy [Text Block]
Entity Filer Category
Entity Filer Category
Income Taxes
Income Tax Policy [Text Block]
Document Fiscal Year Focus
Document Fiscal Year Focus
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]
Number of Options, Vested and expected to vest
Share Based Compensation Arrangement By Share Based Payment Award Options Vested And Expected To Vest Outstanding Number
Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table]
Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table]
Pre-funded warrants to purchase shares
Shares Pre-Funded Warrants To Purchase
Shares pre-funded warrants to purchase.
Construction in Progress
Construction In Progress [Member]
Weighted-average grant date fair value of options granted
Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Weighted Average Grant Date Fair Value
Retained Earnings (Accumulated Deficit), Ending Balance
Retained Earnings (Accumulated Deficit), Beginning Balance
Retained Earnings (Accumulated Deficit), Total
Accumulated deficit
Retained Earnings Accumulated Deficit
Income Taxes
Income Tax Disclosure [Text Block]
Depreciation, Depletion and Amortization, Nonproduction, Total
Depreciation and amortization expense
Depreciation And Amortization
Entity Ex Transition Period
Entity Ex Transition Period
Headquarters Facility
Headquarters Facility [Member]
Headquarters facility.
Fair Value Disclosures [Abstract]
Shares Available for Future Stock Option Grants
Shares Available For Future Stock Option Grants [Member]
Shares available for future stock option grants.
Issuance costs
Temporary Equity Stock Issuance Costs
Temporary equity stock issuance costs.
Maximum
Maximum [Member]
Entity Central Index Key
Entity Central Index Key
Underwriters' option to purchase additional shares
Shares Issued Upon Full Exercise Of Underwriters Option To Purchase Additional Shares
Shares issued upon full exercise of underwriters option to purchase additional shares.
Number of shares vested
Sharebased Compensation Arrangement By Sharebased Payment Award Options Vested Number Of Shares
Operating leases, rent expense recognized
Operating Lease Expense
Temporary Equity [Line Items]
Temporary Equity [Line Items]
Cash and Cash Equivalents
Cash And Cash Equivalents Policy [Text Block]
Schedule of Contractual Maturities of Investments
Investments Classified By Contractual Maturity Date Table [Text Block]
Temporary Equity Disclosure [Abstract]
Entity Tax Identification Number
Entity Tax Identification Number
Equity Component
Equity Component [Domain]
Preferred stock, par value
Preferred Stock Par Or Stated Value Per Share
Expected volatility
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Volatility Rate
Section 162(m) Limitation
Section 162(m) limitation.
Property and Equipment, Net
Property Plant And Equipment Policy [Text Block]
Reverse stock split, conversion ratio
Stockholders Equity Note Stock Split Conversion Ratio1
Income Tax Authority
Income Tax Authority [Domain]
Unrecognized share-based compensation expense, expected to be recognized
Employee Service Share Based Compensation Nonvested Awards Total Compensation Cost Not Yet Recognized Period For Recognition1
Deferred Tax Assets, Tax Deferred Expense, Reserves and Accruals, Total
Accruals & reserves
Deferred Tax Assets Tax Deferred Expense Reserves And Accruals
Deferred tax liabilities:
Accounting standard update adoption date
Change In Accounting Principle Accounting Standards Update Adoption Date
Subsequent Events [Abstract]
Subsequent Event [Line Items]
Leasehold Improvements
Leasehold Improvements [Member]
Statement [Table]
Statement [Table]
Weighted-average remaining lease term (in years)
Operating Lease Weighted Average Remaining Lease Term1
Entity File Number
Entity File Number
Deferred rent and other long-term liabilities
Increase Decrease In Deferred Rent And Other Long Term Liabilities
Increase decrease in deferred rent and other long term liabilities.
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Potential funding period of award to develop vaccine to prevent shingella infections
Potential Funding Period Of Award To Develop Vaccine To Prevent Infections
Potential funding period of award to develop vaccine to prevent infections.
Lessee Lease Description [Line Items]
Lessee Lease Description [Line Items]
Accumulated Deficit
Retained Earnings [Member]
Common stock price per share
Public offering price per share
Shares Issued Price Per Share
Accounting Standards Update
Type Of Adoption [Member]
Accounting Standards Update
Adjustments For New Accounting Pronouncements [Axis]
Payment of issuance costs for initial public offering
Offering expenses
Payments Of Stock Issuance Costs
Increase (Decrease) in Accounts Payable, Total
Accounts payable
Increase Decrease In Accounts Payable
Change in fair value of the redeemable convertible preferred stock tranche liability
Change In Fair Value Of Redeemable Convertible Preferred Stock
Change in fair value of the redeemable convertible preferred stock tranche liability.
Basis of Presentation and Summary of Significant Accounting Policies
Basis Of Presentation And Significant Accounting Policies [Text Block]
Current liabilities:
Liabilities, Current [Abstract]
Cash and cash equivalents, Gross Unrealized Gains
Cash And Cash Equivalents Gross Unrealized Gain Before Tax
Cash and cash equivalents gross unrealized gain before tax.
Equity Incentive Plans
Disclosure Of Compensation Related Costs Share Based Payments [Text Block]
Operating lease, extended maturity date
Lessee Operating Lease Extended Maturity Date
Lessee, operating lease, extended maturity date.
Subsequent Event
Subsequent Event [Member]
Operating lease, renewal option
Lessee Operating Lease Renewal Option
Lessee operating lease renewal option.
Commitments and Contingencies
Commitments And Contingencies Disclosure [Text Block]
Operating lease liabilities
Operating Lease, Liability, Total
Lease liabilities
Operating Lease Liability
Common Stock
Common Stock [Member]
Property, Plant and Equipment, Gross, Ending Balance
Property, Plant and Equipment, Gross, Beginning Balance
Property, Plant and Equipment, Gross, Total
Total property and equipment
Property Plant And Equipment Gross
Professional fees
Accrued Professional Fees Current
Entity Public Float
Entity Public Float
2020 Equity Incentive Plan
Two Thousand Twenty Equity Incentive Plan [Member]
Two thousand twenty equity incentive plan.
Cover [Abstract]
Schedule of Cash, Cash Equivalents And Restricted Cash
Restrictions on Cash and Cash Equivalents [Table Text Block]
Potential funding committed by award
Potential Funding Committed By Award
Potential funding committed by award.
Asset Class
Fair Value By Asset Class [Axis]
Related Party Transaction
Related Party Transaction [Domain]
Proceeds from issuance of redeemable convertible preferred stock, net of issuance costs
Proceeds From Issuance Of Redeemable Convertible Preferred Stock
Accrued legal settlement
Increase Decrease In Accrued Legal Settlement
Increase decrease in accrued legal settlement.
Preferred stock outstanding
Redeemable convertible preferred stock, shares outstanding
Beginning balance, shares
Ending balance, shares
Temporary Equity Shares Outstanding
Statement Of Stockholders Equity [Abstract]
Schedule Of Property Plant And Equipment [Table]
Schedule Of Property Plant And Equipment [Table]
Number of operating segments
Number Of Operating Segments
Disclosure Of Compensation Related Costs Sharebased Payments [Abstract]
Fair value liabilities transferred out of level 3
Fair Value Measurement With Unobservable Inputs Reconciliation Liability Transfers Out Of Level3
Change in Fair Value of Tranche Liability
Effective Income Tax Rate Reconciliation Change In Fair Value Of Tranche Liability
Effective income tax rate reconciliation change in fair value of tranche liability.
Lab Equipment
Lab Equipment [Member]
Lab equipment.
San Carlos
San Carlos [Member]
San Carlos.
Long-Lived Tangible Asset
Property Plant And Equipment By Type [Axis]
Lease termination date
Lease Termination Date
Lease termination date.
Other accrued expenses
Other Accrued Liabilities Current
Document Transition Report
Document Transition Report
Fixed assets
Deferred Tax Assets Property Plant And Equipment
Proceeds from exercise of common stock options
Proceeds From Stock Options Exercised
Operating lease, renewal term
Lessee Operating Lease Renewal Term
Research and development expense to related party
Research And Development Expense To Related Party
Research and development expense to related party.
Additional funding committed by award
Additional Funding Committed By Award
Additional funding committed by award.
Research and development (including related party expenses of $2359, $1,331 and $1,137 in 2021, 2020 and 2019, respectively)
Research and Development Expense, Total
Research And Development Expense
New Accounting Pronouncements Or Change In Accounting Principle [Line Items]
New Accounting Pronouncements Or Change In Accounting Principle [Line Items]
Total stock-based compensation expense
Stock-based compensation expense
Allocated Share Based Compensation Expense
Incentive stock option granted to employees owning percentage of shares of common stock
Incentive Stock Option Granted To Employees Owning Percentage Of Shares Of Common Stock
Incentive stock option granted to Employees Owning percentage of shares of common stock.
Fair value liabilities transferred from level 2 to level 1
Fair Value Liabilities Level2 To Level1 Transfers Amount
Thereafter
Lessee Operating Lease Liability Payments Due After Year Four
Lessee operating lease liability payments due after year four.
Maturities of investments
Proceeds from Maturities, Prepayments and Calls of Debt Securities, Available-for-sale
Capital lease amortization expense
Capital Leases Amortization Expense
Statement Of Financial Position [Abstract]
Available for issuance of shares increased
Share Based Compensation Arrangement By Share Based Payment Award Number Of Shares Increase In Available For Grant
Share based compensation arrangement by share based payment award number of shares increase in available for grant.
Expected dividend yield
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Dividend Rate
Depreciation, Depletion and Amortization, Total
Depreciation and amortization
Depreciation Depletion And Amortization
Amortization of operating right-of-use assets
Operating Lease, Right-of-Use Asset, Amortization Expense
Statutory Rate
Effective Income Tax Rate Reconciliation At Federal Statutory Income Tax Rate
Stockholders' Equity
Stockholders Equity [Abstract]
Warrants
Warrants Disclosure [Text Block]
Warrants.
Long-term Investments, Total
Long-term investments
Long Term Investments
Schedule of Computation of Basic and Diluted Net Loss Per Share
Schedule Of Earnings Per Share Basic And Diluted Table [Text Block]
Weighted-average price per share
Weighted-Average Exercise Price Per Share, Options exercised
Share Based Compensation Arrangements By Share Based Payment Award Options Exercises In Period Weighted Average Exercise Price
2024
Lessee Operating Lease Liability Payments Due Year Three
Entity Common Stock Shares Outstanding
Entity Common Stock, Shares Outstanding
Stock-based Compensation
Effective Income Tax Rate Reconciliation Nondeductible Expense Share Based Compensation Cost
Shares reserved for issuance
Common stock reserved for future issuances
Common Stock Capital Shares Reserved For Future Issuance
Measurement Frequency
Fair Value By Measurement Frequency [Axis]
Award Type
Award Type [Axis]
Entity Shell Company
Entity Shell Company
Average price
Sale Of Stock Price Per Share
Proceeds from initial public offering, net of underwriters' commissions and discounts
Proceeds From Initial Public Offering Net Of Underwriters Commissions And Discounts
Proceeds from initial public offering, net of underwriters' commissions and discounts.
Liabilities, Redeemable Convertible Preferred Stock and Stockholders' Equity
Liabilities and Equity [Abstract]
Icfr Auditor Attestation Flag
ICFR Auditor Attestation Flag
Entity Incorporation State Country Code
Entity Incorporation, State or Country Code
Issuance of common stock under Employee Stock Purchase Plan
Stock Issued During Period Value Employee Stock Purchase Plan
Net Loss Per Share
Earnings Per Share [Text Block]
Counterparty Name
Repurchase Agreement Counterparty Name [Domain]
ROU asset
Deferred Tax Liabilities, Leasing Arrangements
Amendment Flag
Amendment Flag
Due in one to five years
Available For Sale Securities Debt Maturities After One Through Five Years Fair Value
Schedule Of Stock By Class [Table]
Schedule Of Stock By Class [Table]
Product and Service
Product Or Service [Axis]
Conversion of convertible preferred stock into common stock
Conversion Of Stock Amount Converted1
Short-term Investments, Total
Short-term investments
Short Term Investments
Remaining liabilities related to early exercised shares
Remaining Liabilities Related To Early Exercised Shares
Remaining liabilities related to early exercised shares.
Total other income (expense), net
Other Nonoperating Income Expense
Cash and Cash Equivalents, at Carrying Value, Ending Balance
Cash and Cash Equivalents, at Carrying Value, Beginning Balance
Cash and Cash Equivalents, at Carrying Value, Total
Cash and cash equivalents
Cash And Cash Equivalents At Carrying Value
Recently Adopted Accounting Pronouncements
New Accounting Pronouncements Policy Policy [Text Block]
Accrued Research and Development
Accrued Research And Development Policy [Text Block]
Accrued research and development.
Number of operating lease
Number Of Operating Lease
Number of operating lease.
Research credit carryforward
Tax Credit Carryforward Amount
Series A Redeemable Convertible Preferred Stock
Series A Redeemable Convertible Preferred Stock [Member]
Series A redeemable convertible preferred stock.
Fair Value, Recurring
Fair Value Measurements Recurring [Member]
Funding Arrangement [Abstract]
Funding arrangement.
Subsequent Events
Subsequent Events [Text Block]
Net deferred tax asset
Deferred Tax Assets Liabilities Net Before Valuation Allowance
Deferred tax assets liabilities net before valuation allowance.
Fair value assets transferred from level 1 to level 2
Fair Value Assets Level1 To Level2 Transfers Amount
CARB-X Agreement
Combating Antibiotic Resistant Bacteria Biopharmaceutical Accelerator Agreement [Member]
Combating antibiotic resistant bacteria biopharmaceutical accelerator agreement.
Income Tax Disclosure [Table]
Income Tax Disclosure [Table]
Income tax disclosure.
Antidilutive Securities, Name
Antidilutive Securities Name [Domain]
Property Plant And Equipment [Line Items]
Property Plant And Equipment [Line Items]
Other Assets, Noncurrent, Total
Other assets
Other Assets Noncurrent
Collaborative Arrangement and Arrangement Other than Collaborative
Type Of Arrangement [Axis]
Aggregate Intrinsic Value, Exercisable
Sharebased Compensation Arrangement By Sharebased Payment Award Options Exercisable Intrinsic Value1
Employees purchase shares of common stock of lower of fair market value
Sharebased Compensation Arrangement By Sharebased Payment Award Purchase Price Of Common Stock Percent
Prepaid Expenses and Other Current Assets
Prepaid Expenses And Other Current Assets [Member]
Redeemable Convertible Preferred Stock
Redeemable Convertible Preferred Stock [Text Block]
Redeemable convertible preferred stock.
Sale of Stock
Subsidiary Sale Of Stock [Axis]
Summary of Stock-based Compensation Expense
Schedule Of Compensation Cost For Share Based Payment Arrangements Allocation Of Share Based Compensation Costs By Plan Table [Text Block]
Components Of Deferred Tax Assets And Liabilities [Abstract]
Fair Value Measurements and Fair Value of Financial Instruments
Fair Value Disclosures [Text Block]
Proceeds from issuance of common stock under ATM Sales Program, net of issuance costs
Proceeds from issuance of stock, net of commission and offering expenses
Proceeds From Issuance Of Common Stock