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Statements of Operations - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Operating expenses:      
Research and development (including related party expenses of $2359, $1,331 and $1,137 in 2021, 2020 and 2019, respectively) $ 78,411 $ 73,564 $ 45,607
General and administrative 25,259 16,017 8,546
Total operating expenses 103,670 89,581 54,153
Loss from operations (103,670) (89,581) (54,153)
Other income (expense), net:      
Interest expense (7) (7) (40)
Interest income 344 244 632
Grant income 1,585 2,478 237
Realized gains on marketable securities 2    
Foreign currency transaction gains (losses) 1,669 (2,351) (135)
Change in fair value of the redeemable convertible preferred stock tranche liability     3,185
Total other income (expense), net 3,593 364 3,879
Net loss $ (100,077) $ (89,217) $ (50,274)
Net loss per share, basic and diluted $ (1.93) $ (3.02) $ (13.25)
Weighted-average shares outstanding, basic and diluted 51,922,108 29,545,810 3,795,090