Share Capital (Tables)

12 Months Ended

Dec. 31, 2021

Disclosure of classes of share capital [text block] [Abstract]

Schedule of stock option activity

	Number of Stock Options			Weighted Average Exercise Price
Outstanding options, December 31, 2018		65,448		$	49.00
Granted		17,655			59.01
Expired		(518	)		65.57
Outstanding options, December 31, 2019		82,585		$	52.34
Granted		279,190			6.47
Expired/Cancelled		(33,707	)		39.79
Outstanding options, December 31, 2020		328,068		$	13.99
Granted		100,500			11.50
Expired/Cancelled		(14,000	)		16.38
Outstanding options, December 31, 2021		414,568		$	13.88

	Number of options			Weighted average exercise price
Outstanding agent options, December 31, 2018		8,050		$	47.91
Granted		5,025			45.58
Exercised		(5,668	)		43.71
Expired		(810	)		53.00
Outstanding agent options, December 31, 2019		6,597		$	52.68
Granted		445,926			7.36
Outstanding agent options, December 31, 2020		452,523			8.02
Expired		(6,597	)		52.68
Outstanding agent options, December 31, 2021		445,926		$	7.51

	Number of Warrants		Weighted average exercise price
Outstanding, December 31, 2018	149,674		$	60.16
Granted	80,110			54.64
Exercised	(80,865	)		54.64
Expired	(36,920	)		73.22
Outstanding, December 31, 2019	111,999		$	59.02
Granted	3,479,534			8.96
Outstanding, December 31, 2020	3,591,533		$	10.55
Granted	2,142,857			4.00
Exercised	(544,415	)		5.54
Expired	(68,647	)		62.87
Outstanding, December 31, 2021	5,121,328		$	7.64

Schedule stock options outstanding

Grant Date	Number of options outstanding		Number of options exercisable		Weighted Average Exercise Price		Expiry date	Remaining contractual life (years)
1-Jan-17		2,207		2,207	$	40.00	1-Jan-22		0.01	*
11-Jan-17		2,483		2,483		41.00	11-Jan-22		0.03	*
4-Apr-17		6,897		6,897		63.00	4-Apr-22		0.26
24-Jul-17		690		690		79.00	18-Feb-22		0.13	*
24-Jul-17		7,929		7,929		79.00	24-Jul-22		0.56
24-Dec-18		12,896		12,896		57.00	24-Dec-23		1.98
24-Dec-18		1,724		1,724		57.00	18-Feb-22		0.13	*
15-Jan-19		828		828		57.00	15-Jan-24		2.04
21-Mar-19		12,345		12,345		63.00	21-Mar-24		2.22
1-Jan-20		2,069		1,380		57.00	1-Jan-24		2.00
15-Nov-20		95,000		59,375		6.00	15-Nov-30		8.88
15-Nov-20		161,500		100,938		6.00	15-Nov-25		3.88
15-Nov-20		20,000		20,000		6.00	18-Feb-22		0.13	*
2-Jan-21		57,000		28,500		11.50	2-Jan-26		4.01
2-Jan-21		5,000		2,500		11.50	2-Jan-31		8.01
18-Jan-21		14,500		7,250		11.50	18-Jan-26		4.05
18-Jan-21		1,500		1,500		11.50	31-Aug-22		0.67
18-Jan-21		10,000		10,000		11.50	29-Oct-22		0.83
Total		414,568		279,442	$	13.88			4.52

* Expired subsequent to the year end.

Grant Date	Number of options outstanding		Number of options exercisable		Weighted Average Exercise Price		Expiry date	Remaining contractual life (years)
28-Jul-20		1,702		1,702	$	20.49	28-Jul-22		0.57
29-Sep-20		113,500		113,500	$	6.60	28-Sep-25		3.75
29-Sep-20		266,000		266,000	$	6.85	28-Sep-25		3.75
31-Dec-20		64,724		64,724	$	11.50	30-Jun-24		2.50
Total		445,926		445,926		7.51			3.56

Grant Date	Number of Warrants outstanding and exercisable		Exercise Price		Expiry date
23-Dec-19		54,248		51.22		23-Dec-22
28-Jul-20		74,138		20.49		28-Jul-22
29-Sep-20		1,805,585		6.85		28-Sep-25
31-Dec-20		1,294,500		11.50		30-Jun-24
26-Oct-21		1,892,857		4.00		03-Nov-26
Total		5,121,328	$	7.64

Schedule of weighted average assumptions

	2021			2020			2019
Exercise price	$	11.50		$	6.47		$	72.50
Risk-free interest rate		0.23	%		1.68	%		1.5	%
Expected life		5			5			4.8
Annualized volatility		85	%		83	%		143	%
Dividend rate		0.00	%		0.00	%		0.00	%