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Revenues - License and Collaboration Agreement (Details) - USD ($)
6 Months Ended 12 Months Ended
Jan. 02, 2018
Jan. 01, 2018
Oct. 08, 2013
Dec. 21, 2011
Jun. 30, 2018
Jun. 30, 2017
Dec. 31, 2017
Revenue from license and collaboration agreements-third parties              
Accumulated losses         $ (140,890,000)   $ (107,104,000)
License and collaboration agreement with Eli Lilly              
Revenue from license and collaboration agreements-third parties              
Upfront payment         6,500,000    
Development milestone payments achieved as at June 30, 2018         25,000,000    
Remaining development and regulatory approval milestone payments         55,000,000    
Upfront and milestone payments         $ 86,500,000    
Percentage of transaction price allocated to license to fruquintinib         90.00%    
Percentage of transaction price allocated to research and development         10.00%    
Research and development services         $ 5,700,000    
Amortization of upfront payment         200,000    
Amortization of milestone payments         100,000    
License and collaboration agreement with Eli Lilly | ASC 605              
Revenue from license and collaboration agreements-third parties              
Research and development services           $ 6,000,000  
Amortization of upfront payment           500,000  
Milestone revenue           4,500,000  
License and collaboration agreement with Eli Lilly | Maximum              
Revenue from license and collaboration agreements-third parties              
Percentage of royalties     20.00%        
License and collaboration agreement with Eli Lilly | Minimum              
Revenue from license and collaboration agreements-third parties              
Percentage of royalties     15.00%        
License and collaboration agreement with AstraZeneca              
Revenue from license and collaboration agreements-third parties              
Upfront payment         20,000,000    
Development milestone payments achieved as at June 30, 2018         25,000,000    
Remaining development and first-sale milestone payments         95,000,000    
Upfront and milestone payments         $ 140,000,000    
Percentage of transaction price allocated to license to savolitinib         95.00%    
Percentage of transaction price allocated to research and development         5.00%    
Research and development services         $ 2,400,000    
Amortization of upfront payment         100,000    
Amortization of milestone payments         100,000    
License and collaboration agreement with AstraZeneca | ASC 605              
Revenue from license and collaboration agreements-third parties              
Research and development services           1,800,000  
Amortization of upfront payment           100,000  
Milestone revenue           $ 5,000,000  
License and collaboration agreement with AstraZeneca | Adjustments              
Revenue from license and collaboration agreements-third parties              
Accumulated losses             1,200,000
License and collaboration agreement with AstraZeneca | Outside of China              
Revenue from license and collaboration agreements-third parties              
Threshold revenue for tier two royalty rate       $ 5,000,000      
Term of tier two royalty rate       2 years      
License and collaboration agreement with AstraZeneca | PRC              
Revenue from license and collaboration agreements-third parties              
Percentage of royalties       30.00%      
License and collaboration agreement with AstraZeneca | Maximum              
Revenue from license and collaboration agreements-third parties              
Clinical trail costs       $ 50,000,000      
License and collaboration agreement with AstraZeneca | Maximum | Outside of China              
Revenue from license and collaboration agreements-third parties              
Percentage of royalties, tier one       18.00%      
Percentage of royalties, tier two       14.50%      
License and collaboration agreement with AstraZeneca | Minimum | Outside of China              
Revenue from license and collaboration agreements-third parties              
Percentage of royalties, tier one       14.00%      
Percentage of royalties, tier two       10.50%      
ASU 2014-09 | ASC 605              
Revenue from license and collaboration agreements-third parties              
Accumulated losses         (139,974,000)    
ASU 2014-09 | Adjustments              
Revenue from license and collaboration agreements-third parties              
Accumulated losses         $ 916,000    
ASU 2014-09 | License and collaboration agreement with Eli Lilly              
Revenue from license and collaboration agreements-third parties              
Upfront payment $ 6,200,000            
Development milestone payments achieved as at June 30, 2018 23,300,000            
Upfront and milestone payments 29,500,000            
ASU 2014-09 | License and collaboration agreement with Eli Lilly | ASC 605              
Revenue from license and collaboration agreements-third parties              
Upfront payment             5,700,000
Development milestone payments achieved as at June 30, 2018             23,700,000
Upfront and milestone payments             29,400,000
ASU 2014-09 | License and collaboration agreement with Eli Lilly | Adjustments              
Revenue from license and collaboration agreements-third parties              
Upfront payment   $ 500,000          
Development milestone payments achieved as at June 30, 2018   (400,000)          
Upfront and milestone payments   100,000          
ASU 2014-09 | License and collaboration agreement with AstraZeneca              
Revenue from license and collaboration agreements-third parties              
Upfront payment 19,300,000            
Development milestone payments achieved as at June 30, 2018 24,000,000            
Upfront and milestone payments $ 43,300,000            
ASU 2014-09 | License and collaboration agreement with AstraZeneca | ASC 605              
Revenue from license and collaboration agreements-third parties              
Upfront payment             19,600,000
Development milestone payments achieved as at June 30, 2018             24,900,000
Upfront and milestone payments             $ 44,500,000
ASU 2014-09 | License and collaboration agreement with AstraZeneca | Adjustments              
Revenue from license and collaboration agreements-third parties              
Upfront payment   (300,000)          
Development milestone payments achieved as at June 30, 2018   (900,000)          
Upfront and milestone payments   $ (1,200,000)