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Balance Sheet Components - Additional Information (Details) - USD ($)
3 Months Ended 9 Months Ended
Sep. 30, 2018
Sep. 30, 2017
Sep. 30, 2018
Sep. 30, 2017
Property Plant And Equipment [Line Items]        
Loss on disposal of property and equipment     $ 97,000  
Leasehold Improvements        
Property Plant And Equipment [Line Items]        
Incentive received from landlord to construct leasehold improvements     3,200,000  
Leasehold Improvements, Laboratory Equipment and Office Equipment        
Property Plant And Equipment [Line Items]        
Loss on disposal of property and equipment $ 0 $ 0 $ 97,000 $ 0