X0306 4 2022-03-18 0 0001645666 Kezar Life Sciences, Inc. KZR 0001273885 BERGER FRANKLIN M C/O KEZAR LIFE SCIENCES, INC. 4000 SHORELINE COURT, SUITE 300 SOUTH SAN FRANCISCO CA 94080 1 0 0 0 Common Stock 2022-03-18 4 P 0 15000 15.96 A 825691 D Common Stock 2022-03-18 4 P 0 45000 17.00 A 870691 D Common Stock 2022-03-21 4 P 0 20000 14.77 A 890691 D The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $15.47 to $16.36 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the ranges set forth in footnotes (1), (2) and (3). The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $16.885 to $17.01 inclusive. The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $14.44 to $15.00 inclusive. /s/ Marc Belsky, Attorney-in-fact 2022-03-22