Consolidated Statements of Operations - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Operating expenses:
Research and development	$ 38,935	$ 30,981	$ 27,363
General and administrative	15,724	11,969	9,979
Total operating expenses	54,659	42,950	37,342
Loss from operations	(54,659)	(42,950)	(37,342)
Interest income	188	1,208	2,255
Interest expense	(159)
Net loss	$ (54,630)	$ (41,742)	$ (35,087)
Net loss per common share, basic and diluted	$ (1.04)	$ (0.95)	$ (1.84)
Weighted-average shares used to compute net loss per common share, basic and diluted	52,759,335	44,004,190	19,083,826