X0306 4 2021-12-31 false 0001645469 Monopar Therapeutics MNPR 0001362489 Anderson Raymond 1000 SKOKIE BLVD SUITE 350 WILMETTE IL 60091 true false false Common Stock 2021-12-31 4 M false 751 A 5294 D Restricted Stock Units 2021-12-31 4 M false 751 0 D Common Stock 751 0 D Represents shares acquired on vesting and settlement of restricted stock units. On January 26, 2021 the reporting person was granted 3,005 restricted stock units, vesting in four equal quarterly installments with vesting dates on March 31, 2021, June 30, 2021, September 30, 2021, and December 31, 2021. Each restricted stock unit represents a contingent right to receive one share of common stock of the Issuer. Disposed of restricted stock units were surrendered in exchange for issuance of common stock upon vesting and settlement. /s/ Kim R. Tsuchimoto, Attorney-in-fact 2022-01-04