X0508 4 2024-07-01 0001645469 Monopar Therapeutics MNPR 0001573327 Radhakrishnan Karthik 1000 SKOKIE BLVD SUITE 350 WILMETTE IL 60091 1 Chief Financial Officer 0 Stock Options 0.7414 2024-07-01 4 A 0 125000 0 A 2034-06-30 Commom Stock 125000 125000 D On July 1, 2024, the reporting person was granted 125,000 stock options, vesting 6/48ths (15,625 shares) on December 31, 2024, and 1/48th every month thereafter until the stock option is fully vested on July 1, 2028. /s/ Karthik Radhakrishnan 2024-07-03