Share capital - Schedule of Stock Options to Purchase Ordinary Shares (Details) - USD ($) $ / shares in Units, $ in Thousands	12 Months Ended
	Dec. 31, 2024	Dec. 31, 2023	Dec. 31, 2022
Number of options
Number of options, outstanding at beginning of year (in shares)	8,539,507
Number of options, granted (in shares)	3,934,564
Number of options, exercised (in shares)	(235,404)
Number of options, forfeited and cancelled (in shares)	(923,199)
Number of options, outstanding at end of year (in shares)	11,315,468	8,539,507
Number of options, exercisable options (in shares)	6,739,295
Weighted average exercise price
Weighted average exercise price, outstanding at beginning of year (in usd per share)	$ 40.07
Weighted average exercise price, granted (in usd per share)	15.91	$ 55.65	$ 78.69
Weighted average exercise price, exercised (in usd per share)	9.16
Weighted average exercise price, forfeited and cancelled (in usd per share)	51.18
Weighted average exercise price, outstanding at end of year (in usd per share)	31.41	$ 40.07
Weighted average exercise price, exercisable options (in usd per share)	$ 34.68
Aggregate intrinsic value
Aggregate intrinsic value, outstanding	$ 113,849
Aggregate intrinsic value, exercisable options	$ 60,993