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Non-refundable up-front license fee amount.

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Operating lease commitments.

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Percentage of tiered royalty rate of net sales.

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Regulatory and commercial milestone payments.

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Term of lessee's operating lease not yet commenced, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents reported fact of one year, five months, and thirteen days.

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Amount of operating lease expense. Excludes sublease income.

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Minimum amount of purchase arrangement in which the entity has agreed to expend funds to procure goods or services from a supplier.

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Commitments and contingent liabilities - Additional Information (Details) € in Thousands, $ in Thousands		12 Months Ended
	Sep. 10, 2018 USD ($)	Dec. 31, 2024 USD ($)	Dec. 31, 2023 USD ($)	Dec. 31, 2022 USD ($)	Dec. 31, 2024 EUR (€)
Loss Contingencies [Line Items]
Lease not yet commenced, term of contract		20 years			20 years
Lease and rental expense		$ 9,244	$ 8,196	$ 7,108
Pledged bank deposits		4,909	2,848
Operating lease commitments		5,285	3,216
Debt securities, pledge to a bank as guarantee		959,873	$ 910,616
Purchase obligation		52,212
Zai License and Collaboration Agreement
Loss Contingencies [Line Items]
Non-refundable up-front license fee, amount	$ 15,000
Maximum \| Zai License and Collaboration Agreement
Loss Contingencies [Line Items]
Regulatory and commercial milestone payments	$ 78,000
Minimum \| Zai License and Collaboration Agreement \| License
Loss Contingencies [Line Items]
Percentage of tiered royalties rates on net sales	10.00%
Asset Pledged as Collateral
Loss Contingencies [Line Items]
Debt securities, pledge to a bank as guarantee		$ 15,581			€ 15,000