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Income taxes
12 Months Ended
Dec. 31, 2022
Income Tax Disclosure [Abstract]  
Income taxes Income taxes
a.     Tax provision:

As of January 1, 2022, the effective place of daily management and control of the Company moved to Switzerland and the Company has become a Swiss tax resident. As a result, the income tax disclosures have been presented in accordance with the Company’s current country of tax residency.

Income (loss) before income taxes is as follows:
Year ended December 31,
 202220212020
Swiss$(269,621)$(145,591)$32,010 
Non-Swiss187,775 93,516 (13,908)
Total income (loss) before income taxes
$(81,846)$(52,075)$18,102 

The provision (benefit) for income taxes from continuing operations is comprised of:
Year ended December 31,
 202220212020
Current:   
Swiss$469 $281 $3,105 
Non-Swiss10,219 5,995 (4,811)
Total current$10,688 $6,276 $(1,706)
Deferred:
Swiss$— — $— 
Non-Swiss— — — 
Total deferred— — — 
Total income tax provision$10,688 $6,276 $(1,706)
b.     Theoretical tax
The Company's effective tax rate is affected by the tax rates in the various jurisdictions in which the Company operates. Under Swiss law, the Company is subject to income tax at the federal level at a statutory rate of 8.5%, as well as at the cantonal and communal levels, resulting in an aggregate corporate tax rate of 12.0%.

For purposes of comparability, the Company used the Swiss federal statutory rate for the 2022, 2021 and 2020 tax years when presenting the Company's reconciliation of the income tax provision. 
A reconciliation of the provision for income taxes compared with the amounts at the Swiss rate was:
Year ended December 31,
 202220212020
Income (loss) before income taxes$(81,846)$(52,075)$18,102 
Swiss federal statutory rate8.5 %8.5 %8.5 %
Income tax at federal Swiss rate$(6,957)$(4,426)$1,539 
Foreign taxes rate differential25,716 1,601 2,517 
Change in valuation allowance(14,238)11,643 6,821 
Effect of tax law change5,681 — (8,694)
Share based compensation5,318 (4,636)(1,615)
Research and development credits(4,898)(2,216)(5,243)
Return to provision true-ups(1,020)2,416 — 
Withholding taxes548 273 2,366 
Other538 1,621 603 
Income tax$10,688 $6,276 $(1,706)
Effective tax rate(13.1)%(12.1)%(9.4)%
c.     Deferred income tax
Deferred income taxes reflect the net tax effects of temporary differences between the carrying amounts of assets and liabilities for financial purposes and the amounts used for income tax purposes. Significant components of the Company’s deferred tax assets and liabilities are as follows:
December 31,
 20222021
Deferred tax assets:
  Unamortized intangible assets$153,450 $138,978 
Impact of revenue recognition$82,972 $112,251 
  Net operating loss carryforwards$65,472 $77,664 
  Share based compensation$30,009 $25,644 
  Capitalized research and development$16,730 $— 
  Research and development credits$8,992 $12,146 
Lease liabilities$5,846 $4,836 
  Interest limitations$— $7,948 
  Other temporary differences$7,089 $3,032 
Total gross deferred tax assets$370,560 $382,499 
Less: valuation allowance(361,358)(375,717)
Total deferred tax assets9,202 6,782 
Deferred tax liabilities:
Right of use assets5,785 4,559 
Fixed assets1,730 2,214 
Other liabilities1,687 
Total gross deferred tax liabilities$9,202 $6,782 
Net deferred taxes assets (liability)$— $— 
d.     Carryforward loss:
In Switzerland, the Company had $525,131 of net operating carryforwards (NOLs) available at the Federal level, of which $497,371 are available at the cantonal and communal level as well. These NOLs expire from 2026 through
2029. Additionally, the Company had $37,105 of non-Swiss NOLs as of December 31, 2022, of which $4,942 carry forward indefinitely. The remainder expire from 2026 through 2041.
e.     Uncertain tax benefits:
A reconciliation of the beginning and ending balances of uncertain tax benefits is as follows:
 December 31,
 202220212020
Balance at beginning of the year$154 $297 $116 
Additions (reductions) for taxes positions related to prior years(78)(143)181 
Balance at the end of the year$76 $154 $297 
The Company recognizes interest and penalties related to unrecognized tax benefits in tax expense. During the years ended December 31, 2022, 2021 and 2020, the Company accrued $2, $5 and $21, respectively, for interest and penalties expenses related to uncertain tax positions.
The Company files income tax returns in the Switzerland and various foreign jurisdictions. Currently, the Company is under examination by the tax authorities in Israel for the tax years 2018, 2019 and 2020 and is not under examination by any other tax authority. Additional tax years within the period 2016 to 2021 remain subject to examination by Swiss, U.S. and other tax authorities