X0609 4 2026-03-31 false 0001710072 Edgewise Therapeutics, Inc. EWTX 0001644087 Donovan Joanne M. false C/O EDGEWISE THERAPEUTICS, INC. 1715 38TH STREET BOULDER CO 80301 false true false false CMO true Common Stock 2026-03-31 4 M false 21338.00 7.08 A 30935.00 D Common Stock 2026-03-31 4 S false 21338.00 32.1168 D 9597.00 D Stock Option (Right to Buy) 7.08 2026-03-31 4 M false 21338.00 0.00 D 2033-08-17 Common Stock 21338.00 153662.00 D The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 Plan adopted by the Reporting Person on December 26, 2025. The price reported in column 4 is an average price. These shares were sold in multiple transactions at prices ranging from $32.00 to $32.35, inclusive. The Reporting Person undertakes to provide the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. 1/48th of the shares subject to the option vest each month beginning on September 17, 2023, subject to the Reporting Person continuing as a service provider through each vest date. John R. Moore Attorney-in-Fact for Donovan Joanne M. 2026-03-31