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CONSOLIDATED STATEMENTS OF CHANGES IN STOCKHOLDERS' DEFICIT - USD ($)
Common Stock [Member]
Additional Paid-In Capital
Stock Payable
Accumulated Deficit
Noncontrolling Interest
Total
Beginning Balance, Shares at Dec. 31, 2016 23,336,673          
Beginning Balance, Amount at Dec. 31, 2016 $ 23,337 $ 12,412,430 $ (10,718,714) $ 1,717,053
Issuance of common stock for professional services, Shares 564,579          
Issuance of common stock for professional services, Amount $ 565 2,204,435 2,205,000
Warrants granted 1,181,057 1,181,057
Common stock owed but not yet issued (828) 324,995 324,167
Loan discounts 686,538 686,538
Noncontrolling interest of Oak Therapeutics, Inc. 46,884 46,884
Net loss (8,149,885) (8,149,885)
Ending Balance, Shares at Dec. 31, 2017 23,901,252          
Ending Balance, Amount at Dec. 31, 2017 $ 23,902 16,483,632 324,995 (18,868,599) 46,884 (1,989,186)
Issuance of common stock for professional services, Shares 1,871,657          
Issuance of common stock for professional services, Amount $ 1,872 2,275,993 14,583 2,292,448
Warrants granted   662,632       662,632
Issuance of common stock for cancellation of accounts payable, Shares 94,444          
Issuance of common stock for cancellation of accounts payable, Amount $ 94 99,044 99,138
Issuance of common stock for purchase of patents, Shares 170,000          
Issuance of common stock for purchase of patents, Amount $ 170 237,330 42,600 280,100
Issuance of common stock for extension of maturity dates relating to convertible promissory notes, Shares 330,000          
Issuance of common stock for extension of maturity dates relating to convertible promissory notes, Amount $ 330 646,170 646,500
Issuance of common stock for cash, Shares 416,666          
Issuance of common stock for cash, Amount $ 417 499,583 500,000
Beneficial conversion features 1,677,072 1,677,072
Fair value of stock options and restricted stock granted 843,281 843,281
Common stock payable for note conversion 263,397 263,397
Noncontrolling interest of Oak Therapeutics, Inc. (30,472) (30,472)
Net loss (10,400,401) (10,400,401)
Ending Balance, Shares at Dec. 31, 2018 26,784,019          
Ending Balance, Amount at Dec. 31, 2018 $ 26,785 $ 23,424,737 $ 645,575 $ (29,269,000) $ 16,412 $ (5,155,491)