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Stock-Based Compensation (Tables)
 3 Months Ended
Mar. 31, 2022
Share-based Payment Arrangement [Abstract]  
Schedule of Total Stock-Based Compensation
Total stock-based compensation was as follows:
Three Months Ended
March 31,
20222021
(in thousands)
Cost of product revenue$653 $138 
Research and development2,238 1,167 
Sales and marketing3,932 2,057 
General and administrative2,687 1,777 
Total stock-based compensation$9,510 $5,139 
Schedule of Option Activity under 2009 Plan and 2019 Plan
Stock Options
Option activity under the 2009 Plan and 2019 Plan is set forth below:
Shares
Available
for Grant		Number
of Shares		Weighted-
Average
Exercise
Price Per
Share		Weighted-
Average
Remaining
Term		Aggregate
Intrinsic
Value
(in years)(in thousands)
Balance, December 31, 20213,745,216 1,524,985 $6.01 5.76$262,793 
Awards authorized1,063,334 — 
Options exercised— (54,913)7.10 
Options cancelled702 (702)13.19 
Balance, March 31, 20224,809,252 1,469,370 $5.96 5.40$295,930 
Vested and exercisable, March 31, 20221,325,201 $5.37 5.25$267,682 
Vested and expected to vest, March 31, 20221,469,370 $5.96 5.40$295,930 
Schedule of RSU Activity under 2019 Plan
RSU and PRSU activity under the 2019 Plan is set forth below. Grant activity for all PRSUs are disclosed at target (100%):
Restricted Stock UnitsPerformance-Based Restricted Stock Units
Number
of Shares		Weighted-
Average
Grant Date
Fair Value
Per Share		Number
of Shares		Weighted-
Average
Grant Date
Fair Value
Per Share
Balance, December 31, 20211,156,683 $93.27 — $— 
RSUs granted214,988 157.46 35,105 155.03
RSUs forfeited(22,864)146.73 — — 
RSUs vested(210,835)80.63 — — 
Balance, March 31, 20221,137,972 $106.67 35,105 $155.03