X0306 4 2019-06-26 0 0001598646 Minerva Neurosciences, Inc. NERV 0001642053 Kupfer David C/O MINERVA NEUROSCIENCES, INC., 1601 TRAPELO ROAD, SUITE 286 WALTHAM MA 02451 1 0 0 0 Common Stock 2019-06-26 4 P 0 10000 5.55 A 219188 D Common Stock 27935 I By wife The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $5.52 to $5.57, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the range set forth in this footnote (1) to this Form 4. /s/ Marc Recht, Attorney-in-Fact 2019-06-27