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Organization and Business Activities (Details)
$ / shares in Units, $ in Thousands
1 Months Ended 3 Months Ended 6 Months Ended
Aug. 03, 2022
USD ($)
Aug. 03, 2022
USD ($)
shares
Sep. 30, 2021
USD ($)
$ / shares
shares
Jun. 30, 2022
USD ($)
Mar. 31, 2022
USD ($)
Jun. 30, 2021
USD ($)
Mar. 31, 2021
USD ($)
Jun. 30, 2022
USD ($)
shares
Jun. 30, 2021
USD ($)
Jul. 13, 2022
country
Dec. 31, 2021
USD ($)
Dec. 31, 2020
USD ($)
Liquidity                        
Cash and cash equivalents and restricted cash       $ 20,163   $ 61,320   $ 20,163 $ 61,320   $ 47,834 $ 41,590
Proceeds from at-the-market facility               $ 993 $ 37,970      
Shares issued       $ 818 $ 2,221 $ 26,139 $ 37,240          
Lincoln Park Capital Fund, LLC | Purchase agreement | Ordinary shares                        
Liquidity                        
Number of shares issued | shares               7,200,000        
Net proceeds from sale of stock               $ 4,500        
Commitment shares | shares     632,474                  
Commitment share price | $ / shares     $ 0.01                  
Regular purchase     $ 2,500                  
Lincoln Park Capital Fund, LLC | Purchase agreement | Ordinary shares | Maximum                        
Liquidity                        
Shares issued     $ 23,000                  
Lincoln Park Capital Fund, LLC | Purchase agreement | Ordinary shares | Share Price Not Below $0.25 Per Share                        
Liquidity                        
Share price | $ / shares     $ 0.25                  
Lincoln Park Capital Fund, LLC | Purchase agreement | Ordinary shares | Share Price Not Below $0.25 Per Share | Maximum                        
Liquidity                        
Number of shares issued | shares     400,000                  
Lincoln Park Capital Fund, LLC | Purchase agreement | Ordinary shares | Share Price Not Below $2.00 Per Share                        
Liquidity                        
Share price | $ / shares     $ 2.00                  
Lincoln Park Capital Fund, LLC | Purchase agreement | Ordinary shares | Share Price Not Below $2.00 Per Share | Maximum                        
Liquidity                        
Number of shares issued | shares     600,000                  
Lincoln Park Capital Fund, LLC | Purchase agreement | Ordinary shares | Share Price Not Below $3.00 Per Share                        
Liquidity                        
Share price | $ / shares     $ 3.00                  
Lincoln Park Capital Fund, LLC | Purchase agreement | Ordinary shares | Share Price Not Below $3.00 Per Share | Maximum                        
Liquidity                        
Number of shares issued | shares     800,000                  
Open Market Sale Agreement | Jefferies LLC | Ordinary shares                        
Liquidity                        
Number of shares issued | shares               21,214,105        
Proceeds from at-the-market facility               $ 30,100        
Aggregate gross sale proceeds for ordinary shares               $ 31,400        
Subsequent Event                        
Liquidity                        
Number of countries, exclusive rights are distributed. | country                   9    
Number of additional countries rights are distributed | country                   5    
Subsequent Event | Jefferies LLC | At-the-market offering | Maximum                        
Liquidity                        
Ordinary shares remained unsold $ 9,800                      
Subsequent Event | Lincoln Park Capital Fund, LLC | Purchase agreement | Maximum                        
Liquidity                        
Ordinary shares remained unsold $ 18,600                      
Subsequent Event | Open Market Sale Agreement | Jefferies LLC | Ordinary shares                        
Liquidity                        
Number of shares issued | shares   1,963,374                    
Proceeds from at-the-market facility   $ 400                    
Aggregate gross sale proceeds for ordinary shares   $ 400